Registration Dossier
Registration Dossier
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EC number: 227-105-6 | CAS number: 5657-17-0
Endpoint summary
Administrative data
Description of key information
Additional information
Only one acute toxicity study with earthworm is available for H4 EDTA (Edwards, 2009). The EC50 was determined at 156 mg/kg soil dry weight.
In addition two studies with EDTA salts or complexes have been performed in which different end-points (vegetative vigour and seedling emergence) in different plant species was examined. In the 21d veg vigour study (Evangelou et al., 2006) a true NOEC could be established, while in the 14d seedling emergence test (Geebelen et al., 2002) no effect was observed at the highest tested dose. Recalculation of the NOEC from Na2H2 EDTA to H4 EDTA results in a NOEC of 73.1 mg/kg soil dw. For justification for applying the read-across see IUCLID 6, Chapter 13.
The hazard assessment of H4 EDTA reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance. The substance is expected to have a low adsorption potential based on its ionic structure under environmental relevant pH conditions and its low log Kow. The low log Kow indicates that the substance will have a low bioaccumulation potential. There are no further indications that the substance may be hazardous to the environment.
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