Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 701-026-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation: in vitro
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
According to Annex XI(2) of the REACH Regulation "testing for a specific endpoint may be omitted if it is technically not possible to conduct the study as a consequence of the properties of the substance”. And furthermore, Annex VI, Note 1, of the REACH Regulation states: “If it is not technically possible or if it does not appear scientifically necessary to give information the reasons shall be clearly stated in accordance with the relevant provisions.” According to ECHA's Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7a: Endpoint specific guidance (May 2008), section R.7.3.1.3, “Mechanisms of immunologically-mediated hypersensitivity”, the following key steps are required for a chemical to induce sensitisation via skin contact: gaining access to the viable epidermis, protein binding, metabolic activation (if required), internalisation and processing by Langerhans cells (LC), transport of antigen by LC to draining lymph nodes, presentation to and recognition by T lymphocytes (cf. R.7a, p. 259). Non-graphitic carbon fibres within the scope of this registration are a relatively large solid material with a negligible solubility in water and as such they cannot penetrate the skin either by passive diffusion or active transport mechanisms. Consequently, gaining access to the viable epidermis, protein binding, and metabolic activation will not occur with carbon fibres covered by this registration, i.e. all other key steps mentioned above cannot be fulfilled. Therefore, skin sensitising properties of non-graphitic carbon fibres within the scope of this registration can be excluded based on scientific grounds. This assumption is supported by the results from a test with artificial body fluids (see IUCLID section 7.1.1). In this test, the carbon release from the substance was not distinguishable from the blank assuming that no carbon was released. The test substance (milled carbonised PAN based fibre) falls within the typical range of the substance definition including the impurities (in total < 0.3%) which in principle consist of metal and mixed metal oxides (mainly Al, Ca, Fe, Na, and Si oxides). These substances are of negligible concern regarding human health and the environment. In addition, no irritative properties to the skin have been found. The different manufacturing processes and precursor materials for non-graphitic carbon fibres within the scope of this registration lead to slightly different compositions. Accordingly, the choice of the test material is based on the substance with the highest content of nitrogen. Therefore, the obtained test results are regarded to also cover all other qualities of the substance non-graphitic carbon fibre within the scope of this registration. Based on the obtained test results, the explanation in ECHA's guidance document and following the provisions in Annex XI(2) and in Annex VI of the REACH Regulation the information requirement “skin sensitisation” is waived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.