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EC number: 248-053-0 | CAS number: 26850-47-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 22 - September 04, 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.6 (Degradation: Chemical Oxygen Demand)
- Version / remarks:
- 1984;
according to DEV H 41- 1 Deutsche Einheitsverfahren,1980 - Deviations:
- yes
- Remarks:
- Mean of 2 determinations instead of 3
- GLP compliance:
- yes
- Oxygen conditions:
- other: not applicable; chemical oxidation
- Remarks:
- not applicable; chemical oxidation
- Inoculum or test system:
- other: not applicable; chemical oxidation
- Remarks:
- not applicable; chemical oxidation
- Details on inoculum:
- not applicable; chemical oxidation
- Duration of test (contact time):
- 2 h
- Initial conc.:
- 2.5 other: mg
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- other: COD
- Details on study design:
- Not reported
- Reference substance:
- other: potassium hydrogen phthalate
- Remarks:
- Merck No. 4876
- Remarks on result:
- other: for results refer to the section BOD5/COD results
- Key result
- Parameter:
- COD
- Value:
- 1 384 mg O2/g test mat.
- Remarks on result:
- other: Result of COD measurement
- Results with reference substance:
- The COD of the reference substance poatssium hydrogen phthalat is: 199 mg O2/L (Criteria: 200 ± 8 mg O2/L)
- Validity criteria fulfilled:
- not applicable
- Remarks:
- No validity criteria specified in method EU C.9 (1984)
- Interpretation of results:
- other: biodegradation can only be evaluated in connection with BOD measurements
- Conclusions:
- The chemical oxygen demand (COD) of the test substance in the test according to method EU C.9 is 1384 mg O2/g.
- Executive summary:
The chemical oxygen demand (COD) of the test substance was investigated in a test according to method EU C.9.
2.5 mg of the test substance were chemically oxidised with potassium dichromate at 148 +/- 3 °C for 2h. The amount of unreacted potassium dichromate is determined by titration and the COD is calculated from this value. The COD of the test substance was determined to be 1384 mg O2/g under the conditions of this test.
- Endpoint:
- biodegradation in water: screening test, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 26 - December 02, 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- ISO 5815 (Water quality - Determination of Biochemical Oxygen Demand after 5 Days (BOD5) - Dilution and Seeding Method)
- Version / remarks:
- second edition 1989-08-01 (E)
- Deviations:
- yes
- Remarks:
- aerate over night after addition of the inoculum
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: seeding water of an urban waste water
- Details on inoculum:
- not reported
- Duration of test (contact time):
- 5 d
- Initial conc.:
- 806.9 mg/L
- Based on:
- test mat.
- Initial conc.:
- 403.5 mg/L
- Based on:
- test mat.
- Initial conc.:
- 201.7 mg/L
- Based on:
- test mat.
- Initial conc.:
- 100.9 mg/L
- Based on:
- test mat.
- Initial conc.:
- 50.4 mg/L
- Based on:
- test mat.
- Initial conc.:
- 25.2 mg/L
- Based on:
- test mat.
- Initial conc.:
- 12.6 mg/L
- Based on:
- test mat.
- Initial conc.:
- 6.3 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Not reported
- Reference substance:
- other: D(+)-Glucose
- Remarks:
- Merck No. 8337
- Reference substance:
- other: L-Glutamic acid
- Remarks:
- Merck No. 291
- Remarks on result:
- other: for results refer to the section BOD5/COD results
- Key result
- Parameter:
- BOD5
- Value:
- 4 mg O2/g test mat.
- Results with reference substance:
- The BOD5 of glucose-glutamic acid is:
Ref. 1 = 190 mg O2/L
Ref. 2 = 185 mg O2/L
Ref. 3 = 200 mg O2/L - Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The biological oxygen demand after 5 days (BOD5) of the test substance is 4 mg O2/g.
- Executive summary:
The biological oxygen demand after 5 days (BOD5) of the test substance was investigated in a test according to ISO 5815 second edition 1989-08-01 (E).
The test substance was incubated with seeding water of an urban waste water at concetrations ranging between 806.9 and 6.3 mg/L for 5 days at 20 +/- 1 °C without supression of nitrification. Oyxgen measurements were conducted with an oxygen sensitive electrode (SYLAND).
The biological oxygen demand after 5 days (BOD5) of the test substance is 4 mg O2/g.
Referenceopen allclose all
Table 1: COD Analytical Data
Product |
Sample weight [mg] E |
Titration [ml] |
N = |
mg O2/g |
||
a |
b |
c |
||||
Blank |
|
9.930 9.928 Ø = 9.929 |
|
|
|
|
Normality |
|
|
|
10.123 10.119 |
0.1185 0.1185 Ø = 0.1185 |
|
Test item |
2.5 2.5 |
|
6.287 6.271 |
|
|
1381 1387 Ø = 1384 |
Product |
Stock solution [ml] E |
Titration [ml] |
|
mg O2/L |
||
a |
b |
c |
||||
Potassium hydrogen phthalate |
20 20 |
|
5.723 5.724 |
|
|
199 199 Ø = 199 |
Table 1: BOD Analytical Data
Substance |
Test concentration E [mg/L] |
Start mg O2/L T0 |
End mg O2/L T5 |
Blank mg O2/L B1 |
mg O2/g BOD5 |
Test substance |
806.9 |
8.6 |
4.5 |
0.5 |
4 |
8.5 |
4.4 |
0.5 |
4 |
||
403.5 |
8.5 |
6.2 |
0.5 |
4 |
|
8.5 |
6.3 |
0.5 |
4 |
||
201.7 |
8.6 |
7.9 |
0.5 |
1 |
|
8.5 |
8.0 |
0.5 |
0 |
||
100.9 |
8.6 |
8.4 |
0.5 |
0 |
|
8.5 |
8.3 |
0.5 |
0 |
||
50.4 |
8.6 |
8.4 |
0.5 |
0 |
|
8.5 |
8.2 |
0.5 |
0 |
||
25.2 |
8.5 |
8.4 |
0.5 |
0 |
|
8.5 |
8.1 |
0.5 |
0 |
||
12.6 |
8.5 |
8.3 |
0.5 |
0 |
|
8.5 |
8.4 |
0.5 |
0 |
||
6.3 |
8.5 |
8.4 |
0.5 |
0 |
|
8.5 |
7.8 |
0.5 |
32 |
||
Reference |
E [ml/L] |
|
|
|
|
20 |
8.6 |
4.3 |
0.5 |
190 |
|
20 |
8.6 |
4.4 |
0.5 |
185 |
|
20 |
8.6 |
4.1 |
0.5 |
200 |
Description of key information
The chemical oxygen demand (COD) of the test substance was investigated in a test according to method EU C.9 and was determined to be 1384 mg O2/g.
Measurements of the biological oxygen demand after 5 days (BOD5) of the test substance were conducted according to ISO 5815 second edition 1989-08-01 (E) amd resulted in a value of 4 mg O2/g.
The COD is a measure for the amount of organic compounds which can be chemically oxidised. The BOD5 provides information on the amount of biodegradable organic matter.
The BOD5 test is a traditional biodegradation test that is now replaced by the ready biodegradability tests and which should be therefore not be performed today for assessment of the ready biodegradability of substances. In case no other degradability data are available these older test data may however be used.
If substantial degradation occurs within a short time period, the situation may be compared with the criterion BOD5/COD ≥ 0.5. In this case, a compound can be considered readily degradable (and hence rapidly degradable), if:
• the ultimate biodegradability exceeds 50% within 5 days and
• the ultimate degradation rate constant in the test system in this period is greater than 0.1 day-1 corresponding to a half -life of 7 days in the test system.
As the BOD5/COD-ratio of the test substance is 0.003, the test substance can be considered not readily/rapidly biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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