Registration Dossier
Registration Dossier
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EC number: 604-939-2 | CAS number: 154095-77-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- In silico
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Justification for type of information:
- QSAR prediction
Data source
Reference
- Reference Type:
- other: Predicted data
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- (17β)-13-ethyl-3-methoxy-gona-1,3,5(10)-trien-17-yl acetate
- EC Number:
- 604-939-2
- Cas Number:
- 154095-77-9
- Molecular formula:
- C22H30O3
- IUPAC Name:
- (17β)-13-ethyl-3-methoxy-gona-1,3,5(10)-trien-17-yl acetate
- Test material form:
- solid: crystalline
- Details on test material:
- Test item: trienol acetateCas No.: 154095-77-9Batch No.: J65084NStorage: 15-30 °C
Constituent 1
Results and discussion
In vivo
Results
- Remarks on result:
- no indication of irritation
- Remarks:
- QSAR prediction
Any other information on results incl. tables
| Software | Method | Alert | Predicted value |
| ChemProp | Skin irritation and corrosion | No Structural Alerts were found. | Save |
| Toxtree | Skin irritation / skin corrosion | No Structural Alerts were found. | Not Irritating or Corrosive to skin |
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- According to (Q)SAR modells: Toxtree, ChemProp, the predicted values indicated that trienol-acetate is not irritating to skin. The result meets the requirement of No Hazard Category.
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