Registration Dossier
Registration Dossier
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EC number: 207-439-9 | CAS number: 471-34-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- other: Handbook data
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Handbook data - no method specified
- GLP compliance:
- no
- Water solubility:
- 6.6 mg/L
- Temp.:
- 20 °C
- Water solubility:
- 11 mg/L
- Temp.:
- 20 °C
- Details on results:
- The water solubilities of calcium carbonate are:
Aragonite and calcite: 6.6 mg/L at 20 °C
Vaterite: 11 mg/L at 20 °C - Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubilities of calcium carbonate are:
Aragonite and calcite: 6.6 mg/L at 20 °C
Vaterite: 11 mg/L at 20 °C - Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 January 2010 to 04 March 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- 0.017 g/L
- Temp.:
- 20 °C
- pH:
- 9 - 9.4
- Remarks on result:
- other: Mean of 5 samples
- Details on results:
- The results for Samples 1 to 3 suggested that the water solubility was shaking time dependent; therefore, extra testing was carried out using longer shaking periods (Samples 4 and 5). However, the overall results for Samples 1 to 5 indicated that this was not the case.
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of calcium carbonate (conventional) has been determined to be 0.0166 g/L of solution at 20.0 ± 0.5 °C.
Referenceopen allclose all
Table 1: Concentration of test material in the sample solutions
Sample No. |
Time shaken at ~30 °C (hours) |
Time equilibrated at 20 °C (hours) |
Concentration (g/L) |
Solution pH |
1 |
24 |
24 |
1.67 x 10-2 |
9.4 |
2 |
48 |
24 |
1.63 x 10-2 |
9.4 |
3 |
72 |
24 |
2.06 x 10-2 |
9.4 |
4 |
96 |
24 |
1.45 x 10-2 |
9.0 |
5 |
120 |
24 |
1.51 x 10-2 |
9.0 |
Description of key information
The water solubility of bulk calcium carbonate has been determined to be 0.0166 g/L of solution at 20.0 ± 0.5 °C.
Key value for chemical safety assessment
- Water solubility:
- 16.6 mg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of bulk calcium carbonate was determined to be 16.6 mg/L at 20 °C in a GLP study performed in accordance with OECD TG 105 (Walker & White, 2010). This result is supported by data from a peer reviewed handbook showing the solubility to be in the range of 6.6 -11 mg/L at 20 °C.
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