Registration Dossier
Registration Dossier
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EC number: 259-160-7 | CAS number: 54423-67-5
Endpoint summary
Administrative data
Description of key information
Vinyl neononanoate was assessed for eue irritation potential by an U.S.E.P.A. O.T.S. Acute Eye Irritation Testing Guideline study with GLP compliance. The skin irritation potential of vinyl neononanoate was evaluated by both a U.S.E.P.A. O.T.S. and O.E.C.D. Testing Guideline studies conducted with GLP compliance. The U.S.E.P.A. O.T.S. Testing Guideline study applied a more severe occlusice treatment method than did the O.E.C.D. 404 protocol.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Vinyl neononanoate was only slightly irritating to the rabbit eye. Under the conditions of the O.E.C.D. 404 Skin Irritation/Corrosion Testing Guideline study applying semi-occlusive exposure, vinyl neononanoate was only slightly irritating to rabbit skin.
Effects on skin irritation/corrosion: slightly irritating
Effects on eye irritation: slightly irritating
Justification for classification or non-classification
Based on the outcome of GLP Testing Guideline studies vinyl neononanoate does require Classification and Labeling for either Eye or Skin irritation.
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