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EC number: 226-218-8 | CAS number: 5329-14-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
For sulphamidic acid, three short term toxicity tests for aquatic toxicity have been conducted. They are all OECD guideline tests with GLP compliance, which focus on the short-term toxicity of sulphamidic acid to daphnia, algae and microorganisms in sludge respectively. In addition, a well-documented academic literature on short-term toxicity to fish has been adopted in the dossier.
The results of above tests are as follows:
96h LC50 - fish (Pimephales promelas) is 70.3 mg/l;
48h EC50 - Daphnia magna is 71.6 mg/l;
72h ErC50 - algae (Desmodesmus subspicatus) is 48 mg/l, and NOEC of which is 18 mg/l.
3h EC50 - microorganisms in sludge is above 200 mg/l, also the NOEC is above 200 mg/l.
Additionally, long term studies for aquatic toxicity have been performed following approval of testing proposals with daphnia and fish.
In a fish early life stage test according to OECD 210 (GLP-study) no mortality or effects on hatching were seen up to the highest concentration tested. Thus, the NOEC was set to ≥ 60 mg/L in this study.
Following approval of a testing proposal one valid experiment according to OECD 211 was performed using five concentrations (5.6, 11, 19, 34, and 60 mg/L test item) to investigate effects on reproduction to daphnia magna following exposure to sulfamic acid.
Significant decrease in the reproduction of the daphnia could not be observed but in the two highest treatments (34 and 60 mg/L respectively). Therefore, the NOEC was set to 19 mg/L and the LOEC to 34 mg/L in this study. The EC50 was found > 60 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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