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EC number: 226-218-8 | CAS number: 5329-14-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 1.8 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.48 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.18 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 20 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 8.36 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.84 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 5 mg/kg soil dw
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
According to the available toxicity data for aquatic organisms, LC50/EC50 of the short-term toxicity tests for fish, daphnia and algae are 70.3 mg/L, 71.6 mg/L and 48 mg/L, respectively. The lowest value of such is 48 mg/L in algae and is considered as the most relevant information for deriving the PNECaquatic for intermittent release. Based on newly available long-term aquatic toxicity data (NOEC of 60 mg/L in FELS test, 19 mg/L in daphnia reproduction test and 18 mg/L in algae test) the PNECs for freshwater and marine water are derived, according to the assessment method.
As no sediment toxicity data are available and sediment toxicity is very unlikely, due to the very good solubility of the substance in water, a PNEC sediment (freshwater and marine) has been derived by applying the partitioning method in line with the technical guidance document on risk assessment.
As data for soil macroorganisms (NOEC of 290 mg/L soil ww for earthworms) and for soil microorganisms (NOEC of 100 mg/L for nitrification bacteria) as well as for plant toxicity (NOEC of 50 mg/kg soil dw) are available, Then PNECsoil could be derived by the assessment method.
Based on the result of the test for inhibition of oxygen consumption by activated sludge, the NOEC of 200 mg/L is available for deriving PNECstp by the assessment method.
Sulphamidic acid, a very well water soluble inorganic substance, there is no potential for bioaccumulation through the food-chain, and hence secondary poisoning is not relevant to this substance. Therefore, no PNECoral is derived and no risk assessment on secondary poisoning is performed.
Conclusion on classification
However, sulphamidic acid has been added to Annex VI to the CLP Regulation with a harmonized classification with R52/53, or aquatic chronic 3 (H412), respectively. This classification was determined prior to the availability of chronic aquatic toxicity data and thus this harmonized classification should be re-assessed in the light of new data being available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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