Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-399-7 | CAS number: 140-11-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1972
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 972
- Report date:
- 1972
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The test substance was applied to 3 rabbits and their reactions observed for 14 days.
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Benzyl acetate
- EC Number:
- 205-399-7
- EC Name:
- Benzyl acetate
- Cas Number:
- 140-11-4
- Molecular formula:
- C9H10O2
- IUPAC Name:
- benzyl acetate
- Details on test material:
- - Name of test material (as cited in study report): Benzyl Acetate
- Lot/batch No.: RIFM HRB-03-1184
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Benzyl Acetate
- Lot/batch No.: RIFM HRB-03-1184
- Description: Clear colourless liquid
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No information provided
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Details on dermal exposure:
- No information provided
- Duration of exposure:
- No information provided
- Doses:
- 5g/kg body weight
- No. of animals per sex per dose:
- 3 animals used
- Control animals:
- not specified
- Details on study design:
- - Duration of observation period following administration: 14 days
- Statistics:
- No information provided
Results and discussion
- Preliminary study:
- Not relevant
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 other: g/kg body weight
- Based on:
- not specified
- Mortality:
- No deaths observed
- Clinical signs:
- other: No abnormal clinical signs observed
- Gross pathology:
- No information provided
- Other findings:
- No information provided
Any other information on results incl. tables
No information provided
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Based on the results of this study, the LD50 of the test substance was determined to be greater than 5g/kg bodyweight. According to Regulation EC No. 1272/2008, the test substance does not require classification.
- Executive summary:
In a study conducted by Moreno (1972), the test substance, Benzyl Acetate, was applied to 3 rabbits at a dose of 5g/kg body weight. The rabbits were observed for 14 days following application. The study resulted in an LD50 determined to be greater than 5g/kg bodyweight. According to Regulation EC No. 1272/2008, the test substance does not require classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
