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EC number: 233-343-1 | CAS number: 10124-56-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 02 October 2009 and 24 December 2009.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Date of inspection: 2009-09-15 / Date of Signature: 2009-11-26
- Type of method:
- flask method
- Remarks:
- The determination was carried out using the flask method, Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008.
- Key result
- Water solubility:
- >= 54.8 - <= 59.7 other: w/w
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7.2
- Details on results:
- Please see section remarks on results including tables and figures, as the results are mostly tables.
- Conclusions:
- Interpretation of results: very soluble (> 10000 mg/L)
The water solubility of the test material has been visually assessed to be in the range of 54.8 to 59.7 % w/w at 20.0 ± 0.5°C. The temperature range 10 to 30°C had no significant influence on the observed solubility of the test material.
- Executive summary:
Method
The determination was carried out using a flask method, based on Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008.
Conclusion
The water solubility of the test material has been visually assessed to be in the range of 54.8 to 59.7 % w/w at 20.0 ± 0.5°C. The temperature range 10 to 30°C had no significant influence on the observed solubility of the test material (see following table).
Test Temperature
Water Solubility
Typical Solution pH
30.0±0.5°C
In the range 55.2 to 60.0 % w/w
7.2
20.0±0.5°C
In the range 54.8 to 59.7% w/w
7.2
10.0±0.5°C
In the range 50.2 to 54.7 % w/w
7.2
Reference
Results
Preliminary test
The sample concentrations, observations recorded and sample solution pH are shown in the following table:
Sample |
Loading Rate |
Observations |
Solution pH |
1 |
20.6 |
clear colourless mobile liquid |
7.5 |
2 |
31.3 |
clear colourless mobile liquid |
7.4 |
3 |
39.8 |
clear colourless slightly viscous liquid |
7.3 |
4 |
50.6 |
clear colourless slightly viscous liquid |
7.2 |
5 |
60.1 |
opaque viscous liquid |
7.0 |
6 |
22.2 |
clear colourless liquid with no excess test material |
7.6 |
7 |
30.3 |
clear colourless liquid with no excess test material |
7.4 |
8 |
40.3 |
clear colourless slightly viscous liquid with no excess test material |
7.3 |
9 |
49.5 |
clear colourless slightly viscous liquid with no excess test material |
7.2 |
10 |
59.3 |
opaque viscous liquid with excess test material |
7.0 |
11 |
18.8 |
clear colourless liquid with no excess test material |
7.4 |
12 |
29.8 |
clear colourless liquid with no excess test material |
7.2 |
13 |
40.3 |
clear colourless slightly viscous liquid with no excess test material |
7.1 |
14 |
49.3 |
clear colourless slightly viscous liquid with no excess test material |
7.0 |
15 |
59.4 |
opaque viscous liquid with excess test material |
6.9 |
Preliminary test result:
Solubility at 20.0°C: In the range 50.6 to 60.1 % w/w
Solubility at 30.0°C: In
the range 49.5 to 59.3 % w/w
Solubility at 10.0°C: In
the range 49.3 to 59.4 % w/w
1.1.2 Definitive test
The sample concentrations, observations recorded and solution pH are shown in the following table:
Table5.4
Sample |
Loading Rate |
Observations |
Solution pH |
1 |
40.0 |
clear colourless liquid with no excess test material |
7.2 |
2 |
44.8 |
clear colourless liquid with no excess test material |
7.2 |
3 |
50.2 |
clear colourless liquid with no excess test material |
7.2 |
4 |
54.7 |
slightly translucent liquid with excess test material |
* |
5 |
60.5 |
slightly translucent liquid with excess test material |
* |
6 |
39.5 |
clear colourless liquid with no excess test material |
7.2 |
7 |
45.0 |
clear colourless liquid with no excess test material |
7.2 |
8 |
50.0 |
clear colourless liquid with no excess test material |
7.2 |
9 |
54.8 |
clear colourless liquid with no excess test material |
7.2 |
10 |
59.7 |
slightly translucent liquid with excess test material |
* |
11 |
39.6 |
clear colourless liquid with no excess test material |
7.2 |
12 |
45.2 |
clear colourless liquid with no excess test material |
7.2 |
13 |
50.8 |
clear colourless liquid with no excess test material |
7.2 |
14 |
55.2 |
clear colourless liquid with no excess test material |
7.2 |
15 |
60.0 |
slightly translucent liquid with excess test material |
* |
Definitive test
result: Solubility at 10.0°C: In the range 50.2 to 54.7 % w/w
Solubility at 20.0°C: In the
range 54.8 to 59.7 % w/w
Solubility at 30.0°C: In the
range 55.2 to 60.0 % w/w
* Insufficient sample solution for pH measurement
Description of key information
The water solubility was determined according to EU Method A.6 (Water solubility) and under the conditions of GLP.
Key value for chemical safety assessment
Additional information
The water solubility of the test material has been visually assessed to be in the range of 54.8 to 59.7 % w/w at 20.0 ± 0.5°C. The temperature range 10 to 30°C had no significant influence on the observed solubility of the test material.
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