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EC number: 289-214-5 | CAS number: 86261-90-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 (72 hours, biomass) was 379 mg/L and the EC50 (0 - 72 hours, growth rate) was 719 mg/L for ureido methacrylate with Selenastrum capricornutum.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 719 mg/L
- EC10 or NOEC for freshwater algae:
- 97 mg/L
Additional information
A study was conducted to assess the inhibitory effect of ureido methacrylate on the growth of the unicellular green alga Selenastrum capricornutum, Strain No. CCAP 278/4. This study was conducted in accordance with the test guidelines EC Methods for Determination of Ecotoxicity Annex to Directive 92/69/EEC Part C, Method 3 "Algal Inhibition Test" and OECD Guideline for Testing of Chemicals No. 201 "Alga, Growth Inhibition Test". Triplicate algal cultures, with an initial cell count of approximately 1E04 cells/mL, were exposed to ureido methacrylate at nominal test concentrations of 10, 100, 220, 460 and 1000 mg/L. Actual mean measured test concentrations were 10, 97, 206, 430 and 942 mg/L. Mean measured concentrations, which ranged from 92 - 103% of their nominal values at 0 hours and 93 -102% of their nominal values at 72 hours. These cultures, together with one untreated control group of six replicates, were incubated in a Gallenkamp illuminated orbital incubator under continuous illumination at 23-24°C for 72 hours. Cell numbers were counted daily to monitor growth. Environmental conditions, light intensity and temperature, remained within the ranges specified by the protocol throughout duration of the study.
All test and control cultures were inspected microscopically at 72 hours. No abnormalities were detected in any of the cultures examined. No cultures showed any signs of contamination by foreign algal cells or protozoa. The EC50 (72 hours, biomass) was 379 mg/L and the EC50 (0 - 72 hours, growth rate) was 719 mg/L for ureido methacrylate with Selenastrum capricornutum.
Supporting study
The determination fo the growth inhibition of the freshwater algae Pseudokrichneriella subcapitata exposed to the test item Hydroxyethylimidazolidone Methacrylate for a duration of 72 hours was performed to OECD Guideline 201. The EC50 (72 h, growth) was 480 mg/l and the EC10 (72h, growth) was 210 mg/l.
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