Registration Dossier
Registration Dossier
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EC number: 401-670-0 | CAS number: 79456-26-1 ACTF; P-007
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Not known whether GLP or not
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- 1984
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-chloro-5-trifluoromethyl-2-pyridylamine
- EC Number:
- 401-670-0
- EC Name:
- 3-chloro-5-trifluoromethyl-2-pyridylamine
- Cas Number:
- 79456-26-1
- Molecular formula:
- C6H4ClF3N2
- IUPAC Name:
- 3-chloro-5-(trifluoromethyl)pyridin-2-amine
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- At start and finish of the exposure period
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
Study design
- Test type:
- static
Test conditions
- Hardness:
- CaCO3 63 mg/l
- Nominal and measured concentrations:
- Loss in concentration of test substance over test period: 23%
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 23 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 20 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- 20 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 20 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 29 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- 96-h, LC50, Oncorhynchus mykiss: 20 mg/l
- Executive summary:
96-h LC50, Oncorhynchus mykiss: 20 mg/l
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