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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not known whether GLP or not

Data source

Referenceopen allclose all

Reference Type:
other company data
Title:
Unnamed
Title:
Unnamed
Year:
1987

Materials and methods

Test guideline
Guideline:
OECD Guideline 305 D (Bioaccumulation: Static Fish Test)
Version / remarks:
1981
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloro-5-trifluoromethyl-2-pyridylamine
EC Number:
401-670-0
EC Name:
3-chloro-5-trifluoromethyl-2-pyridylamine
Cas Number:
79456-26-1
Molecular formula:
C6H4ClF3N2
IUPAC Name:
3-chloro-5-(trifluoromethyl)pyridin-2-amine

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Route of exposure:
aqueous
Test type:
static
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
8 d

Test conditions

Hardness:
250 mg CaCO3/l
Test temperature:
23-25°C
pH:
7.8 - 8
Details on test conditions:
Magnetic stirring
Nominal and measured concentrations:
0.05 and 0.5 mg/l (nominal)
Measured 67.3-67.4% decrease of concentration during test period
Assay medium not renewed

Results and discussion

Lipid content
Lipid content:
33 %
Time point:
end of exposure
Bioaccumulation factoropen allclose all
Type:
BCF
Value:
15.6
Basis:
whole body w.w.
Time of plateau:
8 d
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:0.05 mg/l
Type:
BCF
Value:
8
Basis:
whole body w.w.
Time of plateau:
8 d
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:0.5 mg/l
Details on results:
Concentration in fish in steady state: 0.249 mg/kg after 8 days at 0.05 mg/l and 0.938 mg/kg after 8 days at 0.5 mg/l.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Not bioaccumulating
Executive summary:

Not bioaccumulating