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EC number: 603-373-3 | CAS number: 129909-90-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 8 April to 6 May 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study in accordance with generally accepted scientific standards and described in sufficient detail
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 123-1 (Seedling Emergence Tier II)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 123-1 (Vegetative Vigor Tier II)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 4-amino-N-tert-butyl-5-oxo-3-(propan-2-yl)-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide
- EC Number:
- 603-373-3
- Cas Number:
- 129909-90-6
- Molecular formula:
- C10H19N5O2
- IUPAC Name:
- 4-amino-N-tert-butyl-5-oxo-3-(propan-2-yl)-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide
- Details on test material:
- - Name of test material (as cited in study report): MKH 3586 70WG
- Substance type: Formulated product
- Physical state: Tan granules
- Composition of test material, percentage of components: 71.1% amicarbazone
- Batch No.: 703-0090
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Analytical dose verification was carried out for the test solutions
Test substrate
- Vehicle:
- no
- Details on preparation and application of test substrate:
- - Method of application to soil surface (if used): Spray application
- Concentration of vehicle in test medium (stock solution and final test solution): Highest rate tested = 1.5 g product in 1
Test organisms
open allclose all
- Species:
- Allium cepa
- Plant group:
- Monocotyledonae (monocots)
- Species:
- Beta vulgaris
- Plant group:
- Dicotyledonae (dicots)
- Species:
- Brassica napus
- Plant group:
- Dicotyledonae (dicots)
- Species:
- Daucus carota
- Plant group:
- Dicotyledonae (dicots)
- Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
- Species:
- Lolium perenne
- Plant group:
- Monocotyledonae (monocots)
- Species:
- Lycopersicon esculentum
- Plant group:
- Dicotyledonae (dicots)
- Species:
- Zea mays
- Plant group:
- Monocotyledonae (monocots)
- Species:
- Glycine max (G. soja)
- Plant group:
- Dicotyledonae (dicots)
- Species:
- Avena sativa
- Plant group:
- Monocotyledonae (monocots)
- Species:
- other: Fagopyrum esculentum
- Plant group:
- Monocotyledonae (monocots)
Study design
- Test type:
- seedling emergence toxicity / vegetative vigour test
- Study type:
- extended laboratory study
- Substrate type:
- natural soil
- Limit test:
- no
- Total exposure duration:
- 21 d
Test conditions
- Details on test conditions:
- TEST SYSTEM
- Testing facility: Bayer Corporation
- Test container (type, material, size): 9 cm dimameter x 8 cm tall for canola, carrot, lettuce, oat, onion, perrennial ryegrass sugar beet and tomato, 10.5 cm diameter x 12 cm tall for buckwheat, corn and soyabean.
- No. of seeds per container: Seedling emergence: for corn and soyabean, 2 seeds per container; for the other species, 5 seeds per container
- No. of plants (retained after thinning): No thinning
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Geographic location: Johnson County., USA
- Pesticide use history at the collection site: Not stated
- Collection procedures: Not stated
- Sampling depth (cm): Not stated
- Soil texture (if natural soil)
- % sand: 60
- % silt: 24
- % clay: 16
- Soil taxonomic classification: Sandy loam
- Soil classification system: Not stated
- Composition (if artificial substrate): NA
- Organic carbon (%): 2.5
- Maximum water holding capacity (in % dry weigth): Not stated
- CEC: 12.7
GROWTH CONDITIONS
- Photoperiod: At least 12 hours
- Light source: Natural light suplemented with sodium vapour lamps
- Light intensity and quality:
- Day/night temperatures:
- Relative humidity (%):
- Wind velocity:
- Air exchange rate:
- Watering regime and schedules:
- Water source/type:
- Volume applied:
- Interval of applications:
- Method of application:
- Any pest control method/fertilization (if used):
ACCLIMATION PERIOD:
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
- Phytotoxicity rating system (if used):
VEHICLE CONTROL PERFORMED: yes/no
TEST CONCENTRATIONS
- Spacing factor for test concentrations:
- Justification for using less concentrations than requested by guideline:
- Range finding study
- Test concentrations:
- Results used to determine the conditions for the definitive study: - Nominal and measured concentrations:
- Application rates: 1, 2, 4, 8, 16, 31, 63, 125 and 250 g a.i./ha
Results and discussion
Any other information on results incl. tables
Table 1: NOEC and ER50 values for vegetative vigour and seedling emergence assessments
Species |
Vegetative vigour |
Seedling emergence |
||
NOEC (g a.i./ha) |
ER50 (g a.i./ha) |
NOEC (g a.i./ha) |
ER50 (g a.i./ha) |
|
Fagopyrum esculentum(buckwheat)a |
2 |
8.8 |
- |
- |
Brassica napus(oilseed rape)a |
16 |
>63 |
31 |
79.5 |
Daucus carota(carrot)bc |
- |
- |
31 |
260 |
Lactuca sativa(lettuce)a |
4 |
12.2 |
63 |
131 |
Glycine max(soya bean)a |
16 |
54.7 |
250 |
>250 |
Beta vulgaris(sugar beet)bc |
2 |
14.6 |
16 |
74.1 |
Lycopersicon esculentum(tomato)a |
8 |
29.5 |
63 |
>250 |
Zea mays(maize)a |
63 |
>250 |
250 |
>250 |
Avena sativa(oat)bd |
63 |
>250 |
>250 |
>250 |
Alium cepa(onion)a |
16 |
56.6 |
146 |
>250 |
Lolium perenne(perennial ryegrass)a |
63 |
235 |
250 |
>250 |
a= endpoint based on dry weight
b= endpoint based on dry weight for vegetative vigour
c= endpoint based on survival for seedling emergence
d= endpoint based on shoot height for seedling emergence
Applicant's summary and conclusion
- Conclusions:
- Seedling emergence test: There were no statistically significant adverse effects on persent seedling emergence as compared to the controls for any species tested. Sugar beet was the most sensitive species tested with an ER50 value of 74.1 g a.i./ha
Vegetative vigour test: Buckwheat was the most sensitive species tested with an ER50 value of 8.8 g a.i./ha - Executive summary:
In a non-target plant study with amicarbazone, lowest ER50 values of 74.1 g a.i./ha (sugar beet) and 8.8 g a.i./ha (buckwheat) were obtained for seedling emergence and vegetative vigour, respectively.
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