Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-581-0 | CAS number: 108-42-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Remarks:
- in vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
- Principles of method if other than guideline:
- The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
- GLP compliance:
- not specified
- Justification for non-LLNA method:
- not specified
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
- Reading:
- other: not specified
- Group:
- test chemical
- Remarks on result:
- positive indication of skin sensitisation
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
- Executive summary:
The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
Migrated from Short description of key information:
The test substance 3-chloroaniline was found to be a skin sensitizer.
Justification for selection of skin sensitisation endpoint:
The substance 3-chloroaniline showed skin sensitizing action in a valid maximization test on guinea pigs.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The test substance 3-chloroaniline is considered as sensitising for the purpose of classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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