3-diethylaminophenol

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: non-GLP guideline study, no chemical control analysis

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method C.2 (Acute Toxicity for Daphnia)

Version / remarks:

Cited as Directive 84/449/EEC, C.2 (Acute toxicity for Daphnia)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

3-diethylaminophenol

EC Number:

202-090-9

EC Name:

3-diethylaminophenol

Cas Number:

91-68-9

Molecular formula:

C10H15NO

IUPAC Name:

3-(diethylamino)phenol

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Details on test solutions:

The substance concentration in the stock solution was 180 mg/L. This solution was stirrd for 1020 min at 330 +/- 10 Kelvin. A serial dilution of the substance was prepared by adding 10 ml each for the required testing concentration.

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

TEST ORGANISM
- Common name: Water flea
- Source: Institut National de Recherche Chmique Applicquee, France, kept since 1978 at the BASF environmental laboratories.
- Age at study initiation (mean and range, SD): < 24 h
- Feeding during test: no

ACCLIMATION
- Acclimation period: none

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Test conditions

Hardness:

2.70 +/- 0.5 mMol/L total hardness

Test temperature:

22.5 °C

pH:

8.0 - 8.6

Dissolved oxygen:

7.1 - 8.6

Salinity:

630 µSiemens/cm

Nominal and measured concentrations:

0, 3.125, 6.25, 12.5, 25, 50, 100 mg/L nominal

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

EC0

Effect conc.:

3.125 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Effect concentrations 2

Duration:

48 h

Dose descriptor:

EC100

Effect conc.:

50 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Effect concentrations 3

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

9.81 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.