Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2007
Bibliographic source:
IUCLID4 data set, 2007

Materials and methods

Test guideline
Guideline:
other: Appraisal of the safety of chemicals in foods, drugs and cosmetics (FDA)
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
CMC (carboxymethyl cellulose)
Doses:
0.71; 1.00; 1.41; 2.00 g/kg bw
No. of animals per sex per dose:
10 animals in total

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
980 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Xn;R22 Criteria used for interpretation of results: EU