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Administrative data

Key value for chemical safety assessment

Additional information

The substance did not show genotoxic effects in an Ames tests with Salmonella typhimurium TA 98, TA 100, TA 1535, TA 1537 and 1538 (50 -5000 microgram/plate), all with and without metabolic activation.

In the attached OECD Toolbox study (read across) for effects in V79 Chinese hamster lung cells, with and without metabolic activation, the results were:

In the first test set with no info on metabolic activation PDPI scored -0.6, ie negative for genotoxicity and cytotoxicity

In the second test set with metabolic activation PDPI scored +0.2, ie ambiguous

In the third test set without metabolic activation PDPI scored -1, ie negative for genotoxicity and cytotoxicity

In addition, the parent substances of this salt (pyromellitic acid and 2 -phenyl-2 -imidazoline) are both negative.


Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

No effects observed, thus no need for classification.