Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1987

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Reference substance name:
Potassium O-isobutyl dithiocarbonate
EC Number:
235-837-2
EC Name:
Potassium O-isobutyl dithiocarbonate
Cas Number:
13001-46-2
IUPAC Name:
potassium O-isobutyl dithiocarbonate
Test material form:
solid: compact
Details on test material:
- Name of test material (as cited in study report):potassium O-isobutyl dithiocarbonate

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
158 mg
Control animals:
yes

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
158 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Conclusions:
The LD50 value of 158 mg/kg was determined in this study by intravenous route of administration
Executive summary:

The LD50 value of 158 mg/kg was determined in this study by intravenous route of administration