Registration Dossier
Registration Dossier
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EC number: 404-360-3 | CAS number: 119313-12-1 CG 25-369; IRGACURE 369; TK 11-319
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Compliance
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 84/449/EWG, C.10 (Hydrolyse)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
- EC Number:
- 404-360-3
- EC Name:
- 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
- Cas Number:
- 119313-12-1
- Molecular formula:
- C23H30N2O2
- IUPAC Name:
- 2-benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one
Constituent 1
Study design
Duration of test
- Duration:
- 5 d
- pH:
- 4
Results and discussion
- Preliminary study:
- At pH 4 and 7 and 50 deg C the hydrolysis is < 10% after 5 days.
Applicant's summary and conclusion
- Conclusions:
- The substance appears to be stable in water in the absence of light
- Executive summary:
Limited information was provided by ECHA, but from the apparent stability in water from this study and from the poor stability as a result of the fish and Daphnia tests, it appears likely that this study was performed in the dark. This is consistent with accepted good practice.
It can be concluded that the substance will degrade in the presence of light in water, but not in the absence of light.
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