Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 247-063-2 | CAS number: 25513-64-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1992-09-22 to 1992-10-20
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-A (Determination of the "Ready" Biodegradability - Dissolved Organic Carbon (DOC) Die-Away Test)
- Version / remarks:
- Cited as Directive 92/69/EEC, C.4-A
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- INOCULUM/TEST ORGANISM
- Sampling site: Municipal WWTP Marl-Ost, sampled 22 Sep 1992
- Preparation of inoculum: sampling, centrifugation (1100 g / 10 min), discard supernatant and resuspend with mineral medium, repeat centrifugation as above, resuspension of sludge (4.9 g dry weight/l), aeration through frit
- Initial cell concentration: 24.5 mg sludge/l - Duration of test (contact time):
- 28 d
- Initial conc.:
- 9.93 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: 2000 ml Erlenmeyer flask covered loosely with aluminum sheet, filled with 900 ml test soln.
- Number of culture flasks per concentration: 2 with test substance (9.93 mg DOC/l) and inoculum; 2 with inoculum only; 2 with control substance
(10.42 mg DOC/l) and inoculum;
- Aeration device: shaking for 28 days
SAMPLING: Days 0, 7, 14, 21, 27, 28
TEST CONDITIONS
- Composition of medium: 10 ml solution A + 1 ml solutions B-D per litre deionized water:
A: 8.5 g KH2PO4, 21.75 g K2HPO4, 33.3 g Na2HPO4 x 2 H2O, 20.0 g (NH4)Cl
B: 22.5 g MgSO4 x 7 H2O; C: 27.5 g CaCl2; D: 0.25 g FeCl3 x 6 H2O
- Test temperature: 21.8 - 22.1 degree C; dark - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 7
- Sampling time:
- 28 d
- Details on results:
- Kinetic of test substance (in %):
= 0 after 14 day(s)
= 0 after 27 day(s)
Degradation products: not measured - Results with reference substance:
- Kinetic of control substance (in %):
= 99 after 7 day(s) - Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- The test substance was determined as not readily biodegradable (7% biodegradation within 28 days)
- Executive summary:
The biodegradability of the test item was examined in a "DOC-DIE AWAY"-test according to EU-Method C.4 -A (Hüls AG 1992). DOC removal was measured at weekly intervals over a period of 28 days. The test item was observed to be "not ready biodegradable" under the present test conditions (7% biodegradation within 28 days). The study was assessed as "reliable without restriction".
Reference
Description of key information
The biodegradability of the test item was examined in a "DOC-DIE AWAY"-test according to EU-Method C.4 -A. DOC removal was measured at weekly intervals over a period of 28 days. Other tests on biodegradability were conducted by Hüls AG 1979 and 1992. The test item was observed to be "not readily biodegradable" under the present test conditions (7% biodegradation within 28 days).
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
Additional information
The biodegradability of the substance was determined in several tests on ready and inherent biodegradation. The DOC die-away test showed that the test substance is not readily biodegradable. Other tests (Zahn-Wellens test, Closed Bottle test and Warburg test) support this finding (degradation rates between 1 and 13 %) and show that the test substance is neither readily nor inherently biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.