Sodium 2(or 5)-[[1-amino-4-[[3-[[(chloroacetyl)amino]methyl]-2,4,6-trimethylphenyl]amino]-9,10-dihydro-9,10-dioxo-2-anthryl]oxy]-5(or 2)-(tert-butyl)benzenesulphonate

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014-08-14

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

German GLP

Type of method:

effusion method: isothermal thermogravimetry

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: AT-29381400
- Expiration date of the lot/batch: May 12, 2019

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At the room temperature (20 °C ± 5 °C), under dark and dry conditions

Temp.:

20 °C

Vapour pressure:

ca. 0.176 Pa

Due to test item properties (water content ≤ 10 % (w/w)) the sample for the measurement was dried at 150 °C. The experiment was done applying temperatures from 170 °C to 200 °C.

The coefficient of correlation (r²) was 0.9394. The coefficient of correlation (r²) was 0.9981. Extrapolation of the curve to 20 °C and fitting this value in the regression curve, a vapour pressure of 1.76 × 10^-1Pawas obtained (mean of three determinations).

Conclusions:

The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of FAT 20200/C TE. The vapour pressure of the test item at 20 °C (293K) was: 0.76 Pa (mean of three determinations, without water).

Executive summary:

The vapour pressure of the test item was determined based on the procedures indicated by the following OECD Guideline 104 and EU Method A.4.

The purpose of the study was to determine the vapour pressure of the test item using the isothermal thermogravimetrical effusion method. The evaporation rates of the test item at elevated temperatures and ambient pressure were determined by monitoring the weight loss.

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of FAT 20200/C TE. According to the information (Proposal for Sameness criteria) the test item FAT 20200/C TE consist of ≤ 10 % (w/w) water. Due to test item properties the test was done above 170 °C with a drying phase at 150 °C for 20 min.

The vapour pressure of the test item at 20 °C (293K) was calculated to: 0.176 Pa (mean of three determinations, without water).

This study is classified acceptable and satisfies the guideline requirements for vapour pressure studies.

Description of key information

The vapour pressure of Acid Violet 109 by isothermal thermogravimetry is 0.176 Pa.
 

Key value for chemical safety assessment

Vapour pressure:

0.176 Pa

at the temperature of:

20 °C

Additional information

The vapour pressure of the test item was determined based on the procedures indicated by the following OECD Guideline 104 and EU Method A.4. The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of FAT 20200/C TE.According to the information (Proposal for sameness criteria) the test item FAT 20200/C consists of ≤ 10 % (w/w) water. Due to test item properties the test was done above 170 °C with a drying phase at 150 °C for 20 min. The vapour pressure of the test item at 20 °C (293K) was calculated to: 0.176 Pa (mean of three determinations, without water). This study is classified acceptable and satisfies the guideline requirements for vapour pressure studies.