Registration Dossier
Registration Dossier
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EC number: 264-092-6 | CAS number: 63310-16-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
3 h EC50 = > 1000 mg/L, NOEC = 1000 mg/L, OECD 209, EPA OPTS 850.6800, Clarke (2002)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
The effect of the test material on the respiration rate of activated sludge was investigated in accordance with standardised guidelines OECD 209 and EPA OPPTS 850.6800. During the study, activated sludge was exposed to a nominal concentrations of the test material of 1000 mg/L with controls and a reference substance (3,5-dichlorophenol) run concurrently for comparison. The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and reference material. Under the conditions of the study, the effect of the test material on the respiration of activated sewage sludge micro-organisms gave a 3 hour EC50 of greater than 1000 mg/L. The No Observed Effect Concentration after 3 hours exposure was 1000 mg/L.
The study was performed in line with GLP and accepted standardised guidelines with a high standard of reporting. The study was assigned a reliability score of 1 and considered suitable for assessment as an accurate reflection of the test material.
The available data are considered to be complete and the result determined, 3 h EC50 value ≥1000 mg/L, was taken forward for risk assessment.
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