Registration Dossier
Registration Dossier
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EC number: 233-971-6 | CAS number: 10476-85-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
The Magnusson & Kligman sensitisation test performed with strontium chloride causes no sensitising effects to skin.
Justification for selection of skin sensitisation endpoint:
Only one study available.
Justification for classification or non-classification
Sensitisation:
The reference Allen (1997) is considered as the key study on skin sensitisation and will be used for classification. The overall sensitisation results are as follows:
The test material, Strontium chloride-6-hydrate extra pure, produced a 0 % (0/10) sensitisation rate and was classified as a non-sensitiser to guinea pig skin. According to the criteria specified by Directive 67/548/EEC and subsequent regulations, the test item is not classified as skin sensitiser. According to the EC Regulation No. 1272/2008 and subsequent regulations, the test item is not classified as Category 1.
Respiratory sensitisation:
Based on an industry survey, during long-year industrial practice no cases of hypersensitivity were observed till now by workers exposed exclusively to strontium chloride. Thus, no classification as respiratory sensitiser according to regulation (EC) 1272/2008 is required.
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