Registration Dossier
Registration Dossier
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EC number: 202-797-2 | CAS number: 99-88-7
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, basic data given acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Daphnia magna test
- Author:
- MOE (Ministry of the Environment in Japan )
- Year:
- 1 998
- Bibliographic source:
- Ministry of the Environment in Japan (http://www.env.go.jp/chemi/sesaku/02e.pdf)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-isopropylaniline
- EC Number:
- 202-797-2
- EC Name:
- 4-isopropylaniline
- Cas Number:
- 99-88-7
- Molecular formula:
- C9H13N
- IUPAC Name:
- 4-(propan-2-yl)aniline
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 21 d
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.005 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 0.016 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
Applicant's summary and conclusion
- Executive summary:
The EC50 (21d Daphnia magna) for 4-isopropylaniline is 0.016 mg/L and the NOEC (21d Daphnia magna) is 0.0051 mg/L. The conducted study followed the OECD guideline 211.
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