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Diss Factsheets
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EC number: 253-211-7 | CAS number: 36788-39-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 2013
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Modelled results using BCFBAF Program (v3.00).
- GLP compliance:
- no
- Radiolabelling:
- no
- Type:
- BCF
- Value:
- 2.876 L/kg
- Basis:
- other: modelled results
- Calculation basis:
- steady state
- Remarks on result:
- other: Log BCF (regression model) =0.459 (BCF = 2.876 L/kg wet-wt)
- Remarks:
- Conc.in environment / dose:not applicable
- Conclusions:
- Using the BCFBAF Program (v3.00) model, a predicted BCF value of 2.876 L/kg wet-wt was obtained using the regression-base model. Similar results were obtained using the Arnot-Gobas methods.
- Executive summary:
All of the modelled results using the BCFBAF 3.0 model showed consistently low estimates for bioaccumulation potential. Additionally, dipropylene glycol, the primary hydrolysis product, has a low potential to bioaccumulation. Based on these results, tris dipropylene glycol is not anticipated to bioaccumulated to any extent and does not meet the criteria in Annex XIII of REACH for bioaccumulation.
Reference
BCFBAF Program (v3.00) Results:
==============================
SMILES : OC(COCC(OP(OC(COCC(O)C)C)OCC(OC(CO)C)C)C)C
CHEM : Tris Dipropylene Glycol Phosphite
MOL FOR: C18 H39 O9 P1
MOL WT : 430.48
--------------------------------- BCFBAF v3.00 --------------------------------
Summary Results: Log BCF (regression-based estimate): 0.46 (BCF = 2.88 L/kg wet-wt)
Biotransformation Half-Life (days) : 0.00923 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 0.11 (BAF = 1.3 L/kg wet-wt)
Log Kow (experimental): not available from database Log Kow used by BCF estimates: 1.20 (user entered) Equation Used to Make BCF estimate: Log BCF = 0.6598 log Kow - 0.333 + Correction Correction(s): Value No Applicable Correction Factors Estimated Log BCF = 0.459 (BCF = 2.876 L/kg wet-wt)
======== Whole Body Primary Biotransformation Rate Estimate for Fish: =========================================================== ------+-----+--------------------------------------------+---------+--------- TYPE | NUM | LOG BIOTRANSFORMATION FRAGMENT DESCRIPTION | COEFF | VALUE ------+-----+--------------------------------------------+---------+--------- Frag | 3 | Aliphatic alcohol [-OH] | -0.0616 | -0.1847 Frag | 2 | Aliphatic ether [C-O-C] | -0.0232 | -0.0465 Frag | 6 | Methyl [-CH3] | 0.2451 | 1.4706 Frag | 6 | -CH2- [linear] | 0.0242 | 0.1451 Frag | 6 | -CH- [linear] | -0.1912 | -1.1474 L Kow| * | Log Kow = 1.20 (user-entered ) | 0.3073 | 0.3688 MolWt| * | Molecular Weight Parameter | | -1.1039 Const| * | Equation Constant | | -1.5058 ============+============================================+=========+========= RESULT | LOG Bio Half-Life (days) | | -2.0349 RESULT | Bio Half-Life (days) | |0.009227 NOTE | Bio Half-Life Normalized to 10 g fish at 15 deg C |
============+============================================+=========+========= Biotransformation Rate Constant: kM (Rate Constant): 75.12 /day (10 gram fish) kM (Rate Constant): 42.24 /day (100 gram fish) kM (Rate Constant): 23.76 /day (1 kg fish) kM (Rate Constant): 13.36 /day (10 kg fish) Arnot-Gobas BCF & BAF Methods (including biotransformation rate estimates): Estimated Log BCF (upper trophic) = 0.115 (BCF = 1.303 L/kg wet-wt) Estimated Log BAF (upper trophic) = 0.115 (BAF = 1.303 L/kg wet-wt) Estimated Log BCF (mid trophic) = 0.137 (BCF = 1.372 L/kg wet-wt) Estimated Log BAF (mid trophic) = 0.137 (BAF = 1.372 L/kg wet-wt) Estimated Log BCF (lower trophic) = 0.140 (BCF = 1.379 L/kg wet-wt) Estimated Log BAF (lower trophic) = 0.140 (BAF = 1.379 L/kg wet-wt) Arnot-Gobas BCF & BAF Methods (assuming a biotransformation rate of zero): Estimated Log BCF (upper trophic) = 0.413 (BCF = 2.588 L/kg wet-wt) Estimated Log BAF (upper trophic) = 0.417 (BAF = 2.613 L/kg wet-wt)
Description of key information
Key value for chemical safety assessment
- BCF (aquatic species):
- 2.88 L/kg ww
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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