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EC number: 230-939-3 | CAS number: 7378-99-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- not specified. To clarify, test material in report described as Farmin DM08P is N,N-dimethyloctan-1-amine (AP-1)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- two vessels prepared containing mineral salts medium, activated sludge (30 mg solids/I; obtained from a domestic sewage
works at Oakley, Suffolk) to give a nominal test concentration of 10 mgC/I. Control vessels comprised two containing inoculated mineral salts medium alone and one containing inoculated mineral salts medium plus sodium benzoate (10 mgC/I).
Sodium benzoate was degraded by 60% after five days and 91% after 29 days. Cumulative CO2 production in the controls after 29 days (91.6 and 90.6 mgCO2) was within the acceptable range for this assay system (recommended maximum = 120 mgC02 for a three litre culture).
The pH oftest mixtures measured at the start and end of the test ranged between 7.6 and 7.7. Temperatures of the test area typically ranged from 19.7 °C to 24.0 °C. Although the lowest value falls outside the minimum recommended for this assay (20°C) it is not
thought to be significant or to have affected the integrity of the test. These results confirm that the inoculum was viable and that the test was valid. - Duration of test (contact time):
- 29 d
- Initial conc.:
- 10 other: mg Carbon/Litre
- Based on:
- other: carbon content of AD-1
- Details on study design:
- The ready biodegradability of Fannin DM08P was assessed in the carbon dioxide (C02) Evolution Test (Modified Sturm Test, Procedure C.4-C of the Annex to Directive 92/69/EEC; OECD Procedure 30 lB).
The total organic carbon (TOC) content of an aqueous solution of Farmin DM08P was determined by using an 0 and I Model 700 organic carbon analyser.
The mean TOC content was 63.3%; this estimate of the carbon content of Farmin DM08P was used to establish test concentrations in the subsequent bacterial inhibition assay and Modified Sturm tests.
A five-day bacterial inhibition test was performed under the conditions of the ClosedBottle Test (EC Procedure C.4-E, OECD Procedure 301D). This showed that the test material at a nominal concentration of 10 mgC/l was not inhibitory to the degradation of the reference material sodium benzoate. In this preliminary test, Fannin DM08P was degraded to 1% of its Chemical Oxygen Demand (COD, 2.53 mgO:z/mg; Huntingdon Life Sciences Report No. 96/KAS 151/0311).
In the Modified Sturm Test, Farmin DM08P was added to two vessels containing mineral salts medium, activated sludge (30 mg solids/I; obtained from a domestic sewage ·works at Oakley, Suffolk) to give a nominal test concentration of 10 mgC/I. Control vessels comprised two containing inoculated mineral salts medium alone and one containing inoculated mineral salts medium plus sodium benzoate (10 mgC/I). Test and control vessels were aerated for 29 days with air that had been treated to remove CO2. The CO2 produced by each culture was trapped in a series of Drechsel bottles containing barium hydroxide which were connected to the outlet from each test vessel. The residual barium hydroxide was determined at intervals by titration. - Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- A five-day bacterial inhibition test was performed under the conditions of the ClosedBottle Test (EC Procedure C.4-E, OECD Procedure 301D). This showed that the test material at a nominal concentration of 10 mgC/l was not inhibitory to the degradation of the reference material sodium benzoate. In this preliminary test, Fannin DM08P was degraded to 1% of its Chemical Oxygen Demand (COD, 2.53 mgO:z/mg; Huntingdon Life Sciences Report No. 96/KAS 151/0311).
- Test performance:
- Sodium benzoate was degraded by 60% after five days and 91% after 29 days. Cumulative C02 production in the controls after 29 days (91.6 and 90.6 mgCO2) was within the acceptable range for this assay system (recommended maximum = 120 mgC02 for a three litre culture).
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 15
- Sampling time:
- 3 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 67
- Sampling time:
- 7 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 98
- Sampling time:
- 29 d
- Details on results:
- Mean cumulative CO2 production by the mixtures containing AD-1 at 10 mgC/l was equivalent to 15% of the theoretical value after three days and 67% after seven days; 98% degradation was achieved after 29 days.
Substances are considered to be readily degradable in this test if CO2 production is equal to or greater than 60% of the theoretical value within ten days of the level achieving 10%.
AD-1 can therefore be considered to be readily degradable. - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The ready biodegradability of AD-1 was assessed in the carbon dioxide (CO2) Evolution Test (Modified Sturm Test, Procedure C.4-C of the Annex to Directive 92/69/EEC; OECD Procedure 301B).
Mean cumulative CO2 production by the mixtures containing AD-1 at 10 mgC/l was equivalent to 15% of the theoretical value after three days and 67% after seven days; 98% degradation was achieved after 29 days.
Substances are considered to be readily degradable in this test if CO2 production is equal to or greater than 60% of the theoretical value within ten days of the level achieving 10%.
AD-1 can therefore be considered to be readily degradable. - Executive summary:
The ready biodegradability of AD-1 was assessed in the carbon dioxide (CO2) Evolution Test (Modified Sturm Test, Procedure C.4-C of the Annex to Directive 92/69/EEC; OECD Procedure 301B).
Mean cumulative CO2 production by the mixtures containing AD-1 at 10 mgC/l was equivalent to 15% of the theoretical value after three days and 67% after seven days; 98% degradation was achieved after 29 days.
Substances are considered to be readily degradable in this test if CO2 production is equal to or greater than 60% of the theoretical value within ten days of the level achieving 10%.
AD-1 can therefore be considered to be readily degradable.
Reference
Description of key information
The ready biodegradability of AD-1 was assessed in the carbon dioxide (CO2) Evolution Test (Modified Sturm Test, Procedure C.4 -C of the Annex to Directive 92/69/EEC; OECD Procedure 301B).
Mean cumulative CO2 production by the mixtures containing AD-1 at 10 mgC/L was equivalent to 15% of the theoretical value after three days and 67% after seven days; 98% degradation was achieved after 29 days.
Substances are considered to be readily degradable in this test if CO2 production is equal to or greater than 60% of the theoretical value within ten days of the level achieving 10%.
AD-1 can therefore be considered to be readily degradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
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