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EC number: 276-012-7 | CAS number: 71786-55-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Not skin irritant
Not eye irritant
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
The study conducted on the test substance underline no effect of irritation adn corrosion on skin and eye.
The irritaton was measured by patch test technique on the intact skin.For erythema the irritation score is 0 in all tested animals.
For edema the irritatione score is 0.3 for #animal1, 0 for #animal2 and 0.3 for #animal3.
The test substance was used undiluited. The eyes of three male rabbits were examined for pre-existing casual injury. 100 mg of the test substance was placed into the conjunctival sac of the right eyes of the animals. The eyelids were then gently held together for two seconds. the left eyes served as control. The eyes were inspected after 24, 48, 72 hours.
To supporting the test substance study a read across study was used. The observed skin irritation consisted of very slight erythema in animal 1, which had resolved whitin 24 hours after exposure. Animals 2 and 3 showed no skin irritation after 4 hours of application of the test substance.
There was no evidence of a corrosive effect on the skin.
Blue staining of the treated skin by the test substance was observed in each animal during the study period of 4 days.
No symptoms of systemic toxicity were observed in the animals during the test period and no mortality occurred.
Installation of the test substance affected the conjunctivae. The irritation of the conjunctivae had resolved within 14 days in all three animals.
There was no evidence of ocular corrosion.
No toxic symptoms were observed in the animals during the test period and no mortality occured.
Justification for classification or non-classification
The study conducted on the test substance underline no effect of irritation adn corrosion on skin and eye.
The irritaton was measured by patch test technique on the intact skin.For erythema the irritation score is 0 in all tested animals.
For edema the irritatione score is 0.3 for #animal1, 0 for #animal2 and 0.3 for #animal3.
The test substance is considered to be a non-irritant according to CLP (CE) n. 1272/2008 criteria.
The test substance was used undiluited. The eyes of three male rabbits were examined for pre-existing casual injury. 100 mg of the test substance was placed into the conjunctival sac of the right eyes of the animals. The eyelids were then gently held together for two seconds. the left eyes served as control. The eyes were inspected after 24, 48, 72 hours.
The test substance is considered to be a non-irritant to the skin according to CLP (CE) n. 1272/2008 criteria.
The observed skin irritation consisted of very slight erythema in animal 1, which had resolved whitin 24 hours after exposure. Animals 2 and 3 showed no skin irritation after 4 hours of application of the test substance.
There was no evidence of a corrosive effect on the skin.
Blue staining of the treated skin by the test substance was observed in each animal during the study period of 4 days.
No symptoms of systemic toxicity were observed in the animals during the test period and no mortality occurred.
According to CLP (CE) n. 1272/2008 criteria the test substance need not to be classified as skin irritant.
Installation of the test substance affected the conjunctivae. The irritation of the conjunctivae had resolved within 14 days in all three animals.
There was no evidence of ocular corrosion.
No toxic symptoms were observed in the animals during the test period and no mortality occured.
According to CLP (CE) n. 1272/2008 criteria, the test substance need not to be classified as eye irritant.
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