Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 235-546-0 | CAS number: 12270-13-2
Endpoint summary
Administrative data
Description of key information
No data on human is available for the target substance. Thus, available data from the chloride salt of the target substance was used in a read-across approach. Details on the read-across rational are provided in section 13. The skin sensitizing potential of the source substance was determined in two Human Repeated Insult Patch Tests (Shelanski, 1971 and Shelanski, 1973) with 200 volunteers each. Both studies showed no visible skin changes in any subjects, except for one volunteer showing a severe reaction (Shelanski, 1973). But, this effect was related to one of the other tested composite materials and not to the source substance.
Additional information
No data is available for the target substance. Thus, available data from the chloride salt of the target substance was used in a read-across approach. Details on the read-across rational are provided in section 13. The skin sensitizing potential of the source substance was determined in two Human Repeated Insult Patch Tests (Shelanski, 1971 and Shelanski, 1973) with 200 volunteers each. Both studies showed no visible skin changes in any subjects, except for one volunteer showing a severe reaction (Shelanski, 1973). But, this effect was related to one of the other tested composite materials and not to the source substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
