Registration Dossier
Registration Dossier
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EC number: 205-521-9 | CAS number: 142-09-6
Specific investigations: other studies
Administrative data
- Endpoint:
- cytotoxicity
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original reference is written in japanese, only short summary in english available.
Data source
Reference
- Reference Type:
- publication
- Title:
- Mechanical properties of resin material using various hydrophobic methacrylate monomers and cytotoxicity of hydrophobic methacrylate monomers on human pulp fibroblasts.
- Author:
- Shimoyama K, Kurata S, Morishita K
- Year:
- 2 002
- Bibliographic source:
- Kanagawa Shigaku 38(1): 1-9
Materials and methods
- Principles of method if other than guideline:
- Six hydrophobic monomers were examined for cytotoxicity on human pulp fibroblasts. The monomers were methyl-(MMA), n-hexyl-(HE), n-dodecyl-(DE), cyclohexyl-(CYE), norbonyl-(NB), phenyl-(PH) and benzyl methacrylate (BE).
- GLP compliance:
- not specified
- Type of method:
- in vitro
Test material
- Reference substance name:
- hexyl 2-methylprop-2-enoate
- EC Number:
- 205-521-9
- Cas Number:
- 142-09-6
- Molecular formula:
- C10H18O2
- IUPAC Name:
- hexyl 2-methylprop-2-enoate
- Test material form:
- liquid
- Details on test material:
- SMILES: CCCCCCOC(=O)C(C)=C
Constituent 1
Results and discussion
Any other information on results incl. tables
The depression of the cell growth was, in order of their concentrations, MMA, CYE, HE, BE, PH, NB,
and DE.
IC50 (n-Hexyl methacrylate): 0.8 mM
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
