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REACH

Dipotassium oxide

EC number: 235-227-6 | CAS number: 12136-45-7

Life Cycle description
Uses advised against

Ecotoxicological information

Toxicity to aquatic plants other than algae

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic plants other than algae

Type of information:

(Q)SAR

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Justification for type of information:

QSAR prediction: US EPA accepted QSAR method for organic chemicals properties assessment.

Qualifier:

according to guideline

Guideline:

other: QSAR

Principles of method if other than guideline:

ECOSAR Program(v1.00)

GLP compliance:

Remarks:

not applicable to QSAR models

Analytical monitoring:

Vehicle:

Test organisms (species):

other: QSAR model

Test type:

other: QSAR model

Water media type:

freshwater

Limit test:

Total exposure duration:

30 d

Hardness:

not applicable. QSAR model

Test temperature:

not applicable. QSAR model

pH:

not applicable. QSAR model

Dissolved oxygen:

not applicable. QSAR model

Salinity:

not applicable. QSAR model

Details on test conditions:

-Name of test material (as cited in study report:Potassium oxide
CAS Number: 12136-45-7
SMILES : KOK
CHEM : Potash (potassium oxide)
MOL FOR: O1 K2
MOL WT : 94.20
Values used to Generate ECOSAR Profile

Log Kow: -1.380 (EPISuite Kowwin v1.68 Estimate)
Wat Sol: 1E+006 (mg/L, EPISuite WSKowwin v1.43 Estimate)

Reference substance (positive control):

Duration:

96 h

Dose descriptor:

EC50

Effect conc.:

1 368.296 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: (Q)SAR prediction

Duration:

30 d

Dose descriptor:

NOEC

Effect conc.:

178.832 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: (Q)SAR prediction

Details on results:

Overview of QSARs estimations on aquatic toxicity of Dipotassium oxide/Potassium oxide

to algae and aquatic plants

Method

Results

Remarks

Reference

QSAR

estimate

Green Algae and Aquatic plants,96-hr EC50 = 1368.296 mg/L (ppm)

Green Algae and Aquatic plants, 30-day, ChV (chronic value) =178.832 mg/L(ppm)

Reliable withrestrictions,

QSAR estimated data

ECOSAR Program (v1.00)

Green Algae and Aquatic plants,96-hrEC50 = 1368.296 mg/L (ppm)

Green Algae and Aquatic plants, 30-day, ChV (chronic value) =178.832 mg/L(ppm)

Validity criteria fulfilled:

yes

Remarks:

US EPA accepted QSAR method for organic chemicals properties assessment.

Conclusions:

Executive summary:

A reliable 96 h LC50 value of 1368.296 mg/L has been calculated for the effects of the test substance towards Green Algae and Aquatic plants. Therefore the test substance has been predicted to be non toxic.

A NOEC value of 178.832 mg/L has been calculated for the effects of the test substance on the mortality of the Green Algae and Aquatic plants. This result signifies that the test substance is not expected to be toxic.

A reliable NOEC value of 178.832 mg/L has been calculated for the effects of the test substance towards Green Algae and Aquatic plants. Therefore the test substance has been predicted to be non toxic.

Description of key information

A 96 h LC50 value of 1368.296 mg/L has been calculated for the effects of the test substance on the mortality of the Green Algae and Aquatic plants. This result signifies that the test substance is not expected to be toxic .
A reliable 96 h LC50 value of 1368.296 mg/L has been calculated for the effects of the test substance towards Green Algae and Aquatic plants. Therefore the test substance has been predicted to be non toxic.
A NOEC value of 178.832 mg/L has been calculated for the effects of the test substance on the mortality of the Green Algae and Aquatic plants. This result signifies that the test substance is not expected to be toxic.
A reliable NOEC value of 178.832 mg/L has been calculated for the effects of the test substance towards Green Algae and Aquatic plants. Therefore the test substance has been predicted to be non toxic.
The available data for saltwater aquatic plants other than algae are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to LC50 following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa.

Key value for chemical safety assessment

EC50 for freshwater plants:: 1 368.296 mg/L
EC50 for marine water plants:: 136.83 mg/L
EC10 or NOEC for freshwater plants:: 178.832 mg/L
EC10 or NOEC for marine water plants:: 17.88 mg/L

Additional information

The available data for saltwater aquatic plants other than algae are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to LC50 following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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