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EC number: 235-227-6 | CAS number: 12136-45-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- other: Published data
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Potassium was added a geometric series of concentrations for obtaining approximation of toxicity. After determination of test concentration, 8 groups of animals were tested at the mean nominal concentrations 54,8 and 102.8 mg potassium /l added to Lake Superior water with 1.2 mg chloride /l. Test concentrations were renewed each week. Test temperature was 18 ±1 oC and photoperiod 18 hours. Reproduction was assessed each week by counting juveniles produced. Three to seven tests were performed and the results of all tests were pooled and statistically analysed.
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Details on test solutions:
- Potassium was added a geometric series of concentrations for obtaining approximation of toxicity. After determination of test concentration, 8 groups of animals were tested at the mean nominal concentrations 54,8 and 102.8 mg potassium /l added to Lake Superior water with 1.2 mg chloride /l. Test concentrations were renewed each week. Test temperature was 18 ±1 oC and photoperiod 18 hours. Reproduction was assessed each week by counting juveniles produced. Three to seven tests were performed and the results of all tests were pooled and statistically analysed.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- SPECIES #
(NAME): 5 Daphnia magna
(Water Flea)
AGE: 12 h
LIFE STAGE: not reported, unknown
COMMENT: NR - Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 21 d
- Hardness:
- 45.3 mg/L CaCO3
- Test temperature:
- 18 °C
- pH:
- 7.74
- Dissolved oxygen:
- 9 mg/L
- Reference substance (positive control):
- not specified
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 68 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- as potassium
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 97 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- as potassium
- Basis for effect:
- immobilisation
- Remarks on result:
- other: 87 mg/l-108 mg/l
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 87 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- as potassium
- Basis for effect:
- immobilisation
- Details on results:
- A 21d NOEC of 68 mg/L has been determined for the effects of the test substance (as potassium) on reproduction of the Daphnia magna.
A 21d NOEC of 87 mg/L has been determined for the effects of the test substance (as potassium) on immobilisation of the Daphnia magna. - Validity criteria fulfilled:
- yes
- Conclusions:
- A 21d NOEC of 68 mg/L has been determined for the effects of the test substance (as potassium) on reproduction of the Daphnia magna.
A 21d NOEC of 87 mg/L has been determined for the effects of the test substance (as potassium) on immobilisation of the Daphnia magna. - Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: US EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- EPI Suite v 4.0/ECOSARv1.00
- GLP compliance:
- no
- Remarks:
- not applicable to QSAR models
- Analytical monitoring:
- not required
- Vehicle:
- not specified
- Test organisms (species):
- other: Daphnid species
- Details on test organisms:
- no further information
- Test type:
- other: QSAR model
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 d
- Hardness:
- not applicable. QSAR model
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Dissolved oxygen:
- not applicable. QSAR model
- Salinity:
- not applicable. QSAR model
- Details on test conditions:
- -Name of test material (as cited in study report:Potassium oxide
CAS Number: 12136-45-7
SMILES : KOK
CHEM : Potash (potassium oxide)
MOL FOR: O1 K2
MOL WT : 94.20
Values used to Generate ECOSAR Profile
Log Kow: -1.380 (EPISuite Kowwin v1.68 Estimate)
Wat Sol: 1E+006 (mg/L, EPISuite WSKowwin v1.43 Estimate) - Reference substance (positive control):
- no
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 273.134 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: cited as a ChV value
- Details on results:
- Daphnid, 30-day,NOEC for freshwater species cited as ChV (chronic value) = 273.134 mg/L (ppm)
- Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- Daphnid, 30-day,NOEC cited as ChV (chronic value) = 273.134 mg/L
- Executive summary:
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 273.134 mg/l .
Referenceopen allclose all
Overview of QSARs estimations on long-term aquatic toxicity of of Dipotassium oxide/Potassium oxide to Daphnid
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Daphnid, 30-day, ChV (chronic value) = 273.134 mg/L (ppm)
Daphnid , 48-hr LC50 = 6675.5 mg/L (ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 273.134mg/l.
Daphnid, 30-day, ChV (chronic value) = 273.134 mg/L (ppm)
Daphnid , 48-hr LC50 = 6675.5 mg/L (ppm)
Description of key information
A 21d NOEC of 68 mg/L has been determined for the effects of the test substance (as potassium) on reproduction of the Daphnia magna.
A 21d NOEC of 87 mg/L has been determined for the effects of the test substance (as potassium) on immobilisation of the Daphnia magna.
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 273.134 mg/l
The available data for saltwater invertebrates are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to NOEC following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa
21-day NOEC(Salt water) =8.7 mg/L (ppm)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 87 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 8.7 mg/L
Additional information
A 21d NOEC of 68 mg/L has been determined for the effects of the test substance (as potassium) on reproduction of the Daphnia magna.
A 21d NOEC of 87 mg/L has been determined for the effects of the test substance (as potassium) on immobilisation of the Daphnia magna.
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 273.134 mg/l
The available data for saltwater invertebrates are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to NOEC following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa
21-day NOEC(Salt water) =8.7 mg/L (ppm)
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