Registration Dossier
Registration Dossier
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EC number: 203-419-9 | CAS number: 106-65-0
Endpoint summary
Administrative data
Description of key information
Additional information
Stability
Stability of the substance in the atmosphere was calculated using the computer program AOPWIN (v 1.92). It is predicted that the substance will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals. The half-life for this reaction in air is estimated to be approximately 336 hours.
In accordance with Column 2 of REACH Annex VIII, testing for hydrolysis as a function of pH need not be conducted as the substance is readily biodegradable
Biodegradation
Ready biodegradability has been determined with activated sludge over a test period of 28 days in a Modified Sturm Test conducted according to OECD test guideline 301 B. Dimethyl succinate is regarded as readily biodegradable.
Simulation tests in water sediment and soil (IUCLID Sections 5.2.2 amd 5.2.3) are waived based on the ready biodegradability of the substance. Values have been calculated using a Fugacity model according to Mackay, Level III using EPIWIN (v.4.11):
Half life in water: 360 hours
Half life in soil: 720 hours
Half life in sediment: 3240 hours
Bioaccumulation
In accordance with REACH Regulation 1907/2006, Annex IX, Column 2, bioaccumulation tests in fish do not need to be conducted as the substance has a low potentail for bioaccumulation based on a log Kow of 0.33
Transport and distribution
In accordance with REACH Regulation 1907 /2006, Annex VIII, Column 2, screening tests for adsorption/desorption do not need to be conducted as the substance has a low potential for adsorption based on a log Kow of 0.33 and the substance degrades rapidly, being readily biodegradable.
Koc has been calculated using the EPA OPERA model. It is predicted that the test material has a Koc of 25.7 L/Kg, supporting the justification for waiving of testing.
According to the McCall classification scheme, this means that dimethyl succinate is very highly mobile (0 < Koc < 50) on soil.
The Henry's Law constant was estimated using the software HENRYWIN (v3.20). The value of 0.0279 Pa m³/mol indicates that the substance is essentially non volatile from surface water.
Distribution in environmental compartments has been calculated using a Fugacity model, under the emission scenario of 1000 kg/h into each of air, water and soil compartments, according to Mackay, Level III. Distribution in various environmental compartments was estimated as: Air= 2.9%; Water= 28.9%; Soil= 68.1% and Sediment= 0.0841%.
Soil and water were then found to be the major target compartments.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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