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EC number: 416-900-5 | CAS number: 79723-02-7 TMAP
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of TMHP to algae was tested in an OECD 201 guideline study in accordance with GLP.
The arithmetic mean measured ErC50 value of TMHP was 0.32 mg/L and the arithmetic mean measured NOErC value of TMHP was 0.063 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.32 mg/L
- EC10 or NOEC for freshwater algae:
- 0.063 mg/L
Additional information
The toxicity of TMHP to algae was tested in an OECD 201 guideline study in accordance with GLP.
The test samples have shown to be stable when prepared in distilled water and there is no evidence that the test material adsorbs to glass. The test samples have, however, been shown unstable when prepared in algal culture media, possible due to formation of a complex with one of the dissolved salts (probably Na2EDTA.2H2O). At t = 0, the measured concentrations were 99 - 103% of nominal. At t = 72h, the measured concentrations were below the LOD (0.0015 mg/L) with the exception of the measured concentration of the sample with the highest nominal concentration: 0.022 mg/L, which can be regarded as negligible.
The authors reported nominal ErC50 and NOErC values for the period 24 -48h of 0.32 and 0.125 mg/L, respectively. It was not reported why this specific period was chosen, as exponential growth was observed during the whole test period. The reviewer accounted for the decline by calculating arithmetic mean measured ErC50 and NOErC values of 0.32 and 0.063 mg/L, respectively, which were furthermore based on growth inhibition during the whole test period (0 -72h). For measured concentrations <LOD at t=72h, a value of LOD/2 (0.00075 mg/L) was taken. Since no analytical measurements were done at t = 24h and t =48h, no TWA mean measured ErC50 and NOErC value could be calculated and a linear decline of test concentrations had to be assumed. Therefore the EC50 value and NOEC value may still be overestimated and the study was assigned a reliability 2.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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