Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14 August 2015 - 9 October 2015
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2016

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: solid
Details on test material:
Lot no. 280001T01O
Purity 100% (m/m)
Molecular formula C8H5ClFN
Molecular mass 169.59 g/mol
Theoretical oxygen demand 2.170 mg O2/mg

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, non-adapted
Duration of test (contact time):
ca. 28 d

Results and discussion

% Degradation
Parameter:
% degradation (O2 consumption)
Value:
-10
Sampling time:
28 d
Remarks on result:
other: no

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
not inherently biodegradable
Conclusions:
PAC-Nitrile is not biodegradable in the Manometric Respirometry Test 301 F within 28 days.
Executive summary:

The biodegradability of PAC-Nitrile exposed to microorganisms derived from activated sludge of a

municipal sewage treatment plant was investigated under aerobic static exposure conditions.

No biodegradability of PAC-Nitrile based on O2 consumption was observed after 28 days as compared

to the theoretical oxygen demand (ThOD).

The procedure control sodium benzoate reached 83% biodegradation after 14 days, thus confirming

suitability of inoculum and test conditions.

PAC-Nitrile is not biodegradable in the Manometric Respirometry Test 301 F within 28 days.