Registration Dossier
Registration Dossier
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EC number: 213-339-6 | CAS number: 938-18-1
Endpoint summary
Administrative data
Description of key information
Additional information
2,4,6-Trimethylbenzoyl chloride hydrolyses readily into 2,4,6-Trimethylbenzoic acid and hydrochloric acid, respectively.
Hydrogen chloride will rapidly dissociate and its effects are the result of pH change. The increase of the concentration of hydrochloric acid in water decreases the pH in the aquatic ecosystem. Generally, the buffer capacity to maintain the pH in the aquatic ecosystem is important and the equilibrium between CO2, HCO3(-) and CO3(2-) in the aquatic ecosystem is mainly responsible for the buffer capacity of receiving water. Considering a buffer capacity of 106 mg/l HCO3- (mean value of 77 european rivers, De Groot and van Dijk 2002; SIDS report for sodium hydroxide, OECD/UNEP 2002) a concentration of 63.3 - 43.9 mg/l HCl is required to reach a final pH of 4.0 - 6.0.
A screening test in Daphnia magna (following the principles of OECD TG 202) resulted in a EC50 (48h) of 21 mg/L (BASF 1999).
Taking the available information into account, the submission item is considered to be acutely harmful to aquatic organisms.
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