Registration Dossier
Registration Dossier
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EC number: 470-710-7 | CAS number: 139122-17-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Annex V
- GLP compliance:
- yes
- Limit test:
- yes
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- Physical form of substance: S
Mass median aerodynamic diameter (for liq.+solid aerosol):
3.4 micron
Constituent 1
Test animals
- Species:
- other: Rat(Sprague-Dawley)
Administration / exposure
- Vehicle:
- other: Compressed air.
- Details on inhalation exposure:
- Dust aerosol atmosphere (nose only)
- Duration of exposure:
- 4 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 2.08 mg/L air
- Exp. duration:
- 4 h
- Mortality:
- Male: 2.08 mg/L; Number of animals: 2; Number of deaths: 0
Female: 2.08 mg/L; Number of animals: 2; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: Occasional or isolated incidents of ptosis, pallor of the extremities and red/brown staining around the snout were also noted. Animals recovered to appear normal one or two days after exposure.
- Gross pathology:
- Effects on organs:
No abnormalities were detected at necropsy.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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