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EC number: 251-073-2 | CAS number: 32509-66-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Boiling pt.:
- ca. 346 - ca. 348 °C
- Atm. press.:
- 1 013.25 hPa
- Conclusions:
- The test item HOSTANOX 0 3 PILLS has a boiling range of 346 - 348°C at atmospheric
pressure (1013.25 hPa). - Executive summary:
In a test according to OECD Test Guideline 103, and EC No. 440/2008 Part A. Method A.2.,
the test item HOSTANOX 0 3 PILLS showed a boiling range at atmospheric pressure
(1013.25 hPa) of 346 - 348 'C.
Reference
Boiling Point
The DSC runs PN4746 and PN4749 in aluminium crucibles under nitrogen are shown in
figure 2. In the temperature range of 70 - 120°C an endothermic effect could be observed. In
correlation with the CoA, supplied by the Study Monitor this effect corresponds to the Glas
Transition of the test item. A second endothermic effect is observed in the temperature range
of 320 - 460°C, which can be attributed to the boiling of the test item.
In both measurements a mass loss after the complete run in the temperature range from
room temperature to 500°C of 88 - 90 % could be observed.
Table 2: Results on melting and boiling point
No. | Sample weight /mg | Onset /°C | Energy / J/g | |
PN4746 | 12.86 | 70310 (Onset: 347.66) | +20 (endothermic) +370 (endothermic) | |
PN4749 | 12.12 | 70 330 (Onset: 349.13) | +20 (endothermic)+330 (endothermic) |
For the correction of the boiling temperature to normal pressure the test item was assigned
to chemical group 3 (e.g. Esters). According to appendix 8.2 a correction value <jl = 5.50 was
used for a temperature range from 340°C.
The lowest measured onset temperature is corrected to the normal pressure to be 346.85 °C
and the highest onset temperature to be 348.31 °C. The test item has a boiling range of
346 - 348°C at atmospheric pressure (1013.25 hPa).
Measurements by the capillary method:
To verify the results of the DSC-measurement and for clarification of the phase transition of
the first endothermic effect, an additional measurement with the capillary method (Apparatus:
Buchi melting Point B-540) was performed. The temperature range of 40 - 400°C was
investigated. Before the test the pills were grounded by using a pistil and mortar
Description of key information
In a test according to OECD Test Guideline 103, and EC No. 440/2008 Part A. Method A.2.,
the test item HOSTANOX 0 3 PILLS showed a boiling range at atmospheric pressure
(1013.25 hPa) of 346 - 348 'C.
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 347 °C
Additional information
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