Calcium bis[(Z)-N-methyl-N-(1-oxo-9-octadecenyl)aminoacetate]

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

10 - 21 May 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point/Boiling Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Remarks:

Initially assessed by the Siwoloboff method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: SOAP005-2
- Expiration date of the lot/batch: 15 October 2022

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient, stored under nitrogen in a desiccator

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: Following receipt of the test item, it was found that the material readily absorbed moisture in the parent container. Consequently, on advice from the Sponsor, a sub-sample was dried overnight at 100°C and then stored in a desiccator under a headspace of nitrogen.

Decomposition:

yes

Decomp. temp.:

>= 200 °C

Remarks on result:

not determinable

As the boiling tube was heated at 10°C/minute, the sample was observed to darken slightly at temperatures above approximately 170 to 185°C, and then at 196°C there was an expansion of the material with bubbles formed at the base, indicating decomposition. When heating was continued beyond this temperature to 400°C, the sample continued to darken significantly but did not boil at any stage. At the end of the visual assessment the material was dark brown with an upper black surface.

The resulting profile by DSC shows the onset of decomposition at approximately 200°C. During the DSC assessment, the test item was initially described as an amber crystalline solid and following the measurement the material had turned into a black swollen mass which had extruded out of the crucible.                                     

Conclusions:

The boiling temperature of the test item, Calcium bis[(Z)-N-methyl-N-(1-oxo-9-octadecenyl) aminoacetate], was not determinable as the test item decomposed at temperatures above approximately 200°C.

Executive summary:

The boiling point of the test item, Calcium bis[(Z)-N-methyl-N-(1-oxo-9-octadecenyl) aminoacetate], was assessed in an experimental study conducted according to OECD 103 guideline (Dunning 2018). The boiling temperature is defined as the temperature at which the pressure of the saturated vapour of a liquid is equal to the standard pressure. The boiling temperature was initially assessed by the Siwoloboff method using a calibrated digital melting point apparatus. Due to visual signs of decomposition, the test item was also assessed by differential scanning calorimetry (DSC).

The boiling temperature of the test item was not determinable as the test item decomposed at temperatures above approximately 200°C.

The study is GLP-compliant and was conducted according to the standard guideline, therefore is considered reliable without restrictions and suitable as a key study for this endpoint.

Description of key information

The test item decomposed at temperatures above approximately 200°C.

Additional information

The boiling point of the test item was determined in an experimental study conducted according to OECD 103 guideline (Dunning 2018). The boiling temperature was initially assessed by the Siwoloboff method using a calibrated digital melting point apparatus. Due to visual signs of decomposition, the test item was also assessed by differential scanning calorimetry (DSC).

The boiling temperature of the test item was not determinable as the test item decomposed at temperatures above approximately 200°C.

The study is GLP-compliant and was conducted according to the standard guideline, therefore is considered reliable without restrictions and suitable as a key study for this endpoint.