Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
secondary literature
GLP compliance:
no
Test type:
other: unkown
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Dioctyltin di(acetate)
EC Number:
241-555-0
EC Name:
Dioctyltin di(acetate)
Cas Number:
17586-94-6
Molecular formula:
C20H40O4Sn
IUPAC Name:
dioctyltin di(acetate)
Test material form:
liquid
Details on test material:
TK 229 740293

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: aerosol
Type of inhalation exposure:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LC50
Effect level:
430 mg/m³ air
Based on:
test mat.
Exp. duration:
4 h
Clinical signs:
other: (430mg/m3) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

Applicant's summary and conclusion

Interpretation of results:
Category 2 based on GHS criteria
Conclusions:
LC50(mouse)=0.43 mg/L (aerosol)