Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance is hydrolytically unstable (half-life less than 12 hours)
Cross-reference
Reason / purpose for cross-reference:
reference to other study
Reference
Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
yes
Remarks:
see free text
Principles of method if other than guideline:
a) additional pH 1.2
b) only pre-study, based on hydrolysis at once; t(1/2) < 5 min
GLP compliance:
no
Radiolabelling:
no
Analytical monitoring:
yes
Duration:
5 min
pH:
1.2
Temp.:
20 °C
Initial conc. measured:
0.1 mol/L
Remarks:
visible hydrolysis at once
Duration:
5 min
pH:
4
Temp.:
20 °C
Initial conc. measured:
0.1 mol/L
Remarks:
visible hydrolysis at once
Duration:
5 min
pH:
7
Temp.:
20 °C
Initial conc. measured:
0.1 mol/L
Remarks:
visible hydrolysis at once
Duration:
5 min
pH:
9
Temp.:
20 °C
Initial conc. measured:
0.1 mol/L
Remarks:
visible hydrolysis at once
Positive controls:
no
Negative controls:
no
Preliminary study:
xes, visible hydrolysis at once
Transformation products:
yes
No.:
#1
No.:
#2
pH:
1.2
Temp.:
20 °C
Duration:
5 min
Remarks on result:
not determinable because of methodological limitations
Remarks:
very low solubility
pH:
4
Temp.:
20 °C
Duration:
5 min
Remarks on result:
not determinable because of methodological limitations
pH:
7
Temp.:
20 °C
Duration:
5 min
Remarks on result:
not determinable because of methodological limitations
pH:
9
Temp.:
20 °C
Duration:
5 h
Remarks on result:
not determinable because of methodological limitations
Key result
pH:
1.2
Temp.:
20 °C
DT50:
< 5 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
based on solubility
Key result
pH:
4
Temp.:
20 °C
DT50:
< 5 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
based on solubility
Key result
pH:
7
Temp.:
20 °C
DT50:
< 5 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
based on solubility
Key result
pH:
9
Temp.:
20 °C
DT50:
< 5 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
based on solubility
Validity criteria fulfilled:
yes
Conclusions:
dioctyltin di(acetat) hydrolysis at once in contact with water in high molar DOTO / dimeric stannoxane compelex and ehtanol

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion