Registration Dossier
Registration Dossier
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EC number: 248-383-5 | CAS number: 27277-00-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 Jun 2016 to 06 Jul 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- July 1995
- Qualifier:
- according to guideline
- Guideline:
- other: Council Regulation (EC) No 440/2008, Official Journal of the European Union, L 142, 31, p. 1 - 739,
- Version / remarks:
- May 2008
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- Version / remarks:
- August 1996
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 0.49
- Temp.:
- 20 °C
- pH:
- >= 7.02 - <= 7.09
- Conclusions:
- The Log Pow of the test item is determined to be 0.49
- Executive summary:
The 1-octanol / water partition coefficient (Pow) of the test item has been determined using the shake flask method to be: 3.10 (± 0.049); which corresponds to a log Pow of 0.49 at 20 °C.
Reference
Description of key information
Log Kow = 0.49 at 20 °C, OECD 107, GLP, flask method, Halarnakar 2017
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.49
- at the temperature of:
- 20 °C
Additional information
The 1-octanol / water partition coefficient (Pow) of the test item has been determined using the shake flask method to be: 3.10 (± 0.049); which corresponds to a log Pow of 0.49 at 20 °C.
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