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EC number: 245-904-8 | CAS number: 23843-64-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the attached justification in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Reference
Description of key information
EC50 (48h) > 100 mg/L (nominal, OECD 202, RA CAS No. 116912-64-2)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 100 mg/L
Additional information
No reliable data on the toxicity of 1-[3-(trimethoxysilyl)propyl]urea (CAS No. 23843-64-3) to aquatic invertebrates are available. Therefore, good quality data from the analogous substance, ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS No. 116912-64-2), have been read across. Details on read across can be found in IUCLID Section 13.
In a study (2000) according to the guideline OECD 202 and GLP standards, the short term toxicity of the read across substance ureidopropyltrialkoxysilane, mixed methoxy and ethoxy esters (CAS No. 116912-64-2) to aquatic invertebrates was tested. Daphnia magna as the test organism was exposed under static conditions for 48 h to a single nominal test item concentration of 100 mg/L and a blank control. The substance was analytically monitored and samples were collected at the beginning and at the end of the experiment. The substance degraded rapidly within 48 h due to hydrolysis. No toxic effects were observed in the study resulting in an EC50 (48 h) of > 100 mg/L (nominal). The substance was tested in a static system due to its high rate of hydrolytical degradation. With a static system an exposure to both the parent and the hydrolysis products was achieved while none caused toxic effects to fish. The result is considered to be reliable.
No toxic effects to aquatic invertebrates are expected by 1 -[3 -(trimethoxysilyl)propyl]urea (CAS No. 23843-64-3) based on the results obtained for the read across substance.
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