Registration Dossier
Registration Dossier
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EC number: 604-144-0 | CAS number: 139525-77-2
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 1 (reliable without restriction)
- Justification for type of information:
- Testing was conducted using a procedure designed to be compatible with OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 604-144-0
- EC Number:
- 604-144-0
- Cas Number:
- 139525-77-2
- Molecular formula:
- C13H15NO.HCl
- IUPAC Name:
- 604-144-0
- Test material form:
- solid: particulate/powder
- Details on test material:
- White powder
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 1.071
- Temp.:
- 25 °C
- pH:
- >= 5 - <= 9
- Details on results:
- Using the correlation log K/log Pow, the log Pow of the test item MEPHTAMN HCl was calculated as 1.071 +-0.004.
The experimentaly determined value is probably the result for the test item form, i.e. the hydrochloride.
Applicant's summary and conclusion
- Conclusions:
- Using the correlation log K/log Pow, the log Pow of the test item MEPHTAMN HCl was calculated as 1.071 +-0.004.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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