Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-462-3 | CAS number: 107-10-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable publication which meets basic scientific principles. Results only as data tables.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 962
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- see details in remarks on material and methods.
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Propylamine
- EC Number:
- 203-462-3
- EC Name:
- Propylamine
- Cas Number:
- 107-10-8
- Molecular formula:
- C3H9N
- IUPAC Name:
- propan-1-amine
- Details on test material:
- - Name of test material (as cited in study report): Propylamine
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- male
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- not specified
- Duration of exposure:
- 24 h
- Doses:
- no data
- No. of animals per sex per dose:
- 4
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 403 mg/kg bw
- 95% CL:
- 213 - 724
- Remarks on result:
- other: The original value in ml/kg was converted into mg/kg based on the density (d=0.72 g/cm3).
- Mortality:
- no data
- Clinical signs:
- other: no data
- Gross pathology:
- no data
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
