Registration Dossier
Registration Dossier
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EC number: 268-667-2 | CAS number: 68133-24-4
Endpoint summary
Administrative data
Description of key information
Five rats/sex received a single oral dose of the similar substance 1 at 4175 mg/kg bw (vehicle water). No effects on mortality and clinical signs were reported during the 14 day observation period. Necropsy showed reddish discoloration of the kidney. The LD50 is > 4175 mg/kg bw (Ciba 1974). This finding of very low toxicity is confirmed in two additional studies, both indicative for a LD50 of > 5000 mg/kg bw.
Moreover a prediction with the QSAR dyes RC 2.0 Developed by Milano Chemometrics and QASR research group Dept. Earth and Environmental Science, University Milano was performed on Reactive Blue 171, and the substance resulted not classified.
Read across is discussed in section 13.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 4 175 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Based on the available data the substance does not need to be classified for acute toxicity according to Regulation ((EC No 1272/2008 (CLP)
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