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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

OECD Guideline 209, EU Method C.11, US EPA OPPTS 850.6800, GLP, key study, validity 2:
3h-EC50 = 700 mg/L
3h-NOEC = 180 mg/L

Key value for chemical safety assessment

EC50 for microorganisms:
700 mg/L
EC10 or NOEC for microorganisms:
180 mg/L

Additional information

One key study is available to assess the effect of the substance on the respiration of activated sewage sludge. This study was performed according to OECD Guideline 209 (1984), EU Method C.11 and US EPA OPPTS 850.6800, with GLP statement.

Following preliminary range-finding tests, activated sewage sludge was exposed to an aqueous dispersion of the test material at concentrations of 180, 320, 560, 1'000 and 1'800 mg/l for a period of 3 hours at a temperature of approximately 21°C with the addition of a synthetic sewage as a respiratory substrate.

The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and a reference material, 3,5-dichlorophenol.

The effect of the test material on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 of 700 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 180 mg/l.