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EC number: 223-095-2 | CAS number: 3734-33-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in soil
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data is from European Draft Assessment Report
- Justification for type of information:
- Data is from European Draft Assessment Report
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- The study was conducted according to US EPA Pesticide Assessment Guideline, Subdivision N, Environmental Fate: Chemistry, 163-1 (October, 1982).
- GLP compliance:
- not specified
- Test type:
- laboratory
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): N-benzyl-2-[(2,6-dimethylphenyl)amino]-N,N-diethyl-2-oxoethanaminium benzoate hydrate
- Molecular formula: C21H29N2O.C7H5O2
- Molecular weight: 446.58 g/mol
- Smilies notation: CC[N+](CC)(Cc1ccccc1)CC(=O)Nc2c(cccc2C)C.c1ccc(cc1)C(=O)[O-]
- InChl: 1S/C21H28N2O.C7H6O2/c1-5-23(6-2,15-19-13-8-7-9-14-19)16-20(24)22-21-17(3)11-10-12-18(21)4;8-7(9)6-4-2-1-3-5-6/h7-14H,5-6,15-16H2,1-4H3;1-5H,(H,8,9)
- Substance type: organic
- Physical state: White granular solid - Radiolabelling:
- yes
- Oxygen conditions:
- aerobic
- Soil classification:
- not specified
- Soil no.:
- #1
- Soil type:
- sandy loam
- % Clay:
- 13.2
- % Silt:
- 31.6
- % Sand:
- 55.2
- pH:
- 6.3
- Soil no.:
- #2
- Soil type:
- sand
- % Clay:
- 5.5
- % Silt:
- 8
- % Sand:
- 86.4
- pH:
- 4.9
- Soil no.:
- #3
- Soil type:
- sandy loam
- % Clay:
- 16.3
- % Silt:
- 20.2
- % Sand:
- 63.5
- pH:
- 4.5
- Soil no.:
- #4
- Soil type:
- silty clay loam
- % Clay:
- 29.2
- % Silt:
- 60.5
- % Sand:
- 10.3
- pH:
- 7
- Details on soil characteristics:
- SOIL COLLECTION AND STORAGE
- Geographic location:
Soil no:
1. Kitleyknowe
2. Easter Howgate
3. Boghall
4. Balmanno
- Soil preparation (e.g., 2 mm sieved; air dried etc.): Air dried and sieved to less than 5 mm aggregates.
- PROPERTIES OF THE SOILS (in addition to defined fields)
- Moisture content:
Kitleyknowe (Soil 1) Easter Howgate (Soil 2) Boghall (Soil 3) Balmanno (Soil 4)
- 5kPa : 43.1 - 5kPa : 16.3 - 5kPa : 41.9 - 5kPa : 45.8
-33kPa: 33.3 - 33kPa: 16.1 - 33kPa: 36.3 - 33kPa: 33.7
- Soil No.:
- #1
- Duration:
- 30 d
- Soil No.:
- #2
- Duration:
- 30 d
- Soil No.:
- #3
- Duration:
- 30 d
- Soil No.:
- #4
- Duration:
- 30 d
- Soil No.:
- #1
- Initial conc.:
- 4.49 other: mg/g soil
- Based on:
- act. ingr.
- Soil No.:
- #2
- Initial conc.:
- 5.15 other: mg/g soil
- Based on:
- act. ingr.
- Soil No.:
- #3
- Initial conc.:
- 3.73 other: mg/g soil
- Based on:
- act. ingr.
- Soil No.:
- #4
- Initial conc.:
- 4.73 other: mg/g soil
- Based on:
- act. ingr.
- Parameter followed for biodegradation estimation:
- radiochem. meas.
- Details on experimental conditions:
- Soils were brought to a soil moisture content giving a matric tension of -33kPa by addition of water and BITREX solution.
- Soil No.:
- #1
- % Degr.:
- < 20
- Parameter:
- radiochem. meas.
- Sampling time:
- 30 d
- Remarks on result:
- other: Other details not known
- Soil No.:
- #2
- % Degr.:
- < 20
- Parameter:
- radiochem. meas.
- Sampling time:
- 30 d
- Remarks on result:
- other: Other details not known
- Soil No.:
- #3
- % Degr.:
- ca. 60
- Parameter:
- radiochem. meas.
- Sampling time:
- 30 d
- Remarks on result:
- other: Other details not known
- Soil No.:
- #4
- % Degr.:
- < 20
- Parameter:
- radiochem. meas.
- Sampling time:
- 30 d
- Remarks on result:
- other: Other details not known
- Transformation products:
- not specified
- Evaporation of parent compound:
- not specified
- Volatile metabolites:
- not specified
- Residues:
- not specified
- Details on results:
- Recovery of radioactivity in three of the four soils was more than 80% of the applied radioactivity and was recovered in the top 31.5cm of soil However in the Balmanno soil recovery was much lower ca 60%.
- Conclusions:
- According to this study the test substance Denatonium benzoate is not considered to be significantly degraded in soil in 30 days at 15ºC.
- Executive summary:
In study of biodegradation in soil of Denatonium benzoate (BITREX) was observed in 4 types of soil namely 1.Kitleyknowe,2. Easter Howgate, 3. Boghall, 4. Balmanno for 30days. Recovery of radioactivity in three of the four soils was more than 80% of the applied radioactivity(AR) and was recovered in the top 31.5cm of soil However in the Balmanno soil recovery was much lower ca 60%. Therefore it is considered that in the study conducted for 30 days at 15ºC no significant degradation of the active substance occurred in the soil.
Reference
Summary of the recovery of BITREX in the soil columns
Test soil |
Bitrex applied (mg/g soil) |
Total recovery (% AR) |
Recovery in leachate (% AR) |
Kitleyknowe Easter |
5.15
|
92.1
|
0.045
|
Howgate |
4.49 |
82.8 |
0.046 |
Boghall |
3.73 |
96.3 |
10.5 |
Balmanno |
4.73 |
59.5 |
0.035 |
Recovery of radioactivity in three of the four soils was more than 80% of the applied radioactivity (AR) and was recovered in the top 31.5cm of soil. However in the Balmanno soil recovery was much lower ca 60%.
In three of the soils less than 0.05% of BITREX appeared in the leachate after application of Bitrex. This indicates a strong adsorption of BITREX to those soils. However in the Boghall soil about 10% AR appeared in the leachate.
Description of key information
According to this study the test substance Denatonium benzoate is not considered to be a significant degraded substance in 30 days at 15ºC.
Key value for chemical safety assessment
Additional information
In study of biodegradation of soil of Denatonium benzoate (BITREX) was observed in 4 types of soil namely 1.Kitleyknowe,2. Easter Howgate, 3. Boghall, 4. Balmanno for 30days.Recovery of radioactivity in three of the four soils was more than 80% of the applied radioactivity and was recovered in the top 31.5cm of soil However in the Balmanno soil recovery was much lower ca 60%.
Therefore it is considered that in the study conducted for 30 days at 15ºC no significant degradation of the active substance occurred.
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