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Description of key information

Key study: Test method according to EU method C.7, GLP study. The test substance rapidly hydrolyses and half-life < 4 minutes at pH 4 and 7 (23ºC) and pH 9 (27ºC).

Key value for chemical safety assessment

Half-life for hydrolysis:
4 min
at the temperature of:
23 °C

Additional information

Key study: A study was performed to assess the hydrolytic behaviour of OS-2200 with respect to pH. Due to the highly reactive nature of the test substance, a modified test was performed based on EU method C.7, Abiotic degradation: Hydrolysis as a function of pH. Hydrolysis was evaluated after inverting the test substance in the buffer at pH 4, 7 and 9. Analysis was performed by gas chromatography. Under test conditions the test substance rapidly hydrolysed and exhibited half-lives significantly less than one day (<ca 4 minutes) at pH 4 and 7 ( 23ºC) and at pH 9 (27º C).