Registration Dossier
Registration Dossier
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EC number: 202-996-4 | CAS number: 102-01-2
Endpoint summary
Administrative data
Description of key information
skin
KEY_404_1988_Hoechst_88.1832: not corrosive, not irritating
NONKEY_404_1974_Lonza_ 1974-01-17: not corrosive, not irritating
NONKEY_404_1965_Hoechst_1965-11-30: not corrosive, not irritating
eye
KEY_405_1988_Hoechst_88.1865: not irritating
NONKEY_405_1965_Hoechst_ 1965-11-30: not irritating
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin irritation
In a reliable key study no signs of irritation or corrosion were observed (all scores 0). Findings of two non-key studies are not inconsistnet with these data.
Eye irritation
In a reliable key study some rabbits showed only slight responses (mean scores cornea: 0.3, conjunctivae redness: 0.7, conjunctivae chemosis: 0.3) which were fully reversible within 72h. That implies that mean scores for all irritation parameters were below threshold values. Findings of a non-key study are not inconsistent with these data.
Justification for classification or non-classification
Skin irritation
Mean scores for all irritation parameters were below threshold values. Based on that classification is not warrantable.
Eye irritation
Mean scores for all irritation parameters were below threshold values. Based on that classification is not warrantable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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